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11/5/2019 9:02:40 AM | Browse: 166 | Download: 139
Publication Name World Journal of Gastroenterology
Manuscript ID 50392
Country/Territory Italy
2019-08-01 13:12
Peer-Review Started
2019-08-01 13:12
To Make the First Decision
2019-08-28 01:49
Return for Revision
2019-09-04 08:40
2019-09-06 17:15
Second Decision
2019-09-20 09:11
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-09-28 04:43
Articles in Press
2019-09-28 04:43
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2019-10-18 05:03
Publish the Manuscript Online
2019-10-21 09:37
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Basic Study
Article Title Role of tristetraprolin phosphorylation in paediatric patients with inflammatory bowel disease
Manuscript Source Invited Manuscript
All Author List Alessia Di Silvestre, Marianna Lucafò, Letizia Pugnetti, Matteo Bramuzzo, Gabriele Stocco, Egidio Barbi and Giuliana Decorti
Funding Agency and Grant Number
Funding Agency Grant Number
the Italian Ministry of Health projects
Ricerca Corrente 1/17 and 21/17 of the Institute for Maternal and Child Health IRCCS Burlo Garofolo
Corresponding author Giuliana Decorti, MD, Full Professor, Department of Medical, Surgical and Health Sciences, University of Trieste, Institute for Maternal and Child Health - IRCCS “Burlo Garofolo”, Via A. Fleming 22, Trieste, I-34127, Trieste 34127, Italy. decorti@units.it
Keywords Inflammatory bowel disease; Tristetraprolin; 14-3-3 protein; Phosphorylation; Cytokine; Inflammation
Core Tip We report a preliminary study describing the role of tristetraprolin (TTP)/14-3-3 complex in a small cohort of paediatric patients affected by inflammatory bowel disease (IBD). The experiments were conducted on IBD inflamed and non-inflamed colonic tissues and IBD-derived macrophages respect to heathy donors’. This study demonstrates for the first time the relation between the phosphorylation of TTP and paediatric IBD patients. Indeed, a higher expression of TTP/14-3-3 complex was recorder both in inflamed colon specimens compared to non-inflamed and in IBD-derived macrophages respect to healthy donors.
Publish Date 2019-10-21 09:37
Citation Di Silvestre A, Lucafò M, Pugnetti L, Bramuzzo M, Stocco G, Barbi E, Decorti G. Role of tristetraprolin phosphorylation in paediatric patients with inflammatory bowel disease. World J Gastroenterol 2019; 25(39): 5918-5925
Url https://www.wjgnet.com/1007-9327/full/v25/i39/5918.htm
DOI https://dx.doi.org/10.3748/wjg.v25.i39.5918
Full Article (PDF) WJG-25-5918.pdf
Full Article (Word) WJG-25-5918.docx
Manuscript File 50392-Review.docx
Answering Reviewers 50392-Answering reviewers.pdf
Audio Core Tip 50392-Audio core tip.m4a
Biostatistics Review Certificate 50392-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 50392-Conflict-of-interest statement.pdf
Copyright License Agreement 50392-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 50392-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document 50392-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 50392-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 50392-Language certificate.pdf
Peer-review Report 50392-Peer-review(s).pdf
Scientific Misconduct Check 50392-Scientific misconduct check.pdf
Scientific Editor Work List 50392-Scientific editor work list.pdf