Publication Name	World Journal of Meta-Analysis
Manuscript ID	50769
Country	Egypt

Received	2019-08-09 09:03
Peer-Review Started	2019-08-09 09:04
To Make the First Decision	2019-08-26 07:15
Return for Revision	2019-08-26 08:44
Revised	2019-08-31 23:03
Second Decision	2019-09-03 01:17
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2019-09-03 01:50
Articles in Press	2019-09-03 01:50
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2019-09-03 03:19
Publish the Manuscript Online	2019-09-03 07:56

ISSN	2308-3840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Surgery
Manuscript Type	Review
Article Title	Preventive strategies for anastomotic leakage after colorectal resections: A review
Manuscript Source	Invited Manuscript
All Author List	Mostafa Shalaby, Waleed Thabet, Mosaad Morshid, Mohamed Farid and Pierpaolo Sileri
Funding Agency and Grant Number
Corresponding Author	Mostafa Shalaby, MBChB, MD, MSc, PhD, Lecturer, Surgeon, Department of General Surgery, Mansoura University Hospitals, Mansoura University, 60 Elgomhouria Street, Mansoura 35516, Dakahlia, Egypt. mostafashalaby@mans.edu.eg
Key Words	Anastomotic leakage; Colorectal; Resection; Anastomosis; Cancer; Anastomotic disruption
Core Tip	Although the most important prerequisites for the creation of anastomosis is well-perfused and tension-free anastomosis, surgeons have proposed several preventive measures, which were assumed to reduce the incidence of anastomotic leakage, including antibiotic prophylaxis, intraoperative air leak test, omental pedicle flap, defunctioning stoma, pelvic drain insertion, stapled anastomosis, and general surgical technique. However, the decision remains based on the surgeon’s choice. This review found that many preventative measures were employed with no clear evidence supporting the superiority of stapled anastomosis over hand-sewen anastomosis, coating of the anastomosis, or pelvic drain. Defunctioning stoma, when justified it could decrease the leakage-related complications and the incidence of reoperation. Mechanical bowel preparation combined with oral antibiotics still recommended.
Publish Date	2019-09-03 07:56
Citation	Shalaby M, Thabet W, Morshed M, Farid M, Sileri P. Preventive strategies for anastomotic leakage after colorectal resections: A review. World J Meta-Anal 2019; 7(8): 389-398
URL	https://www.wjgnet.com/2308-3840/full/v7/i8/389.htm
DOI	https://dx.doi.org/10.13105/wjma.v7.i8.389

Full Article (PDF)	WJMA-7-389.pdf
Full Article (Word)	WJMA-7-389.docx
Manuscript File	50769-Review.docx
Answering Reviewers	50769-Answering reviewers.pdf
Audio Core Tip	50769-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	50769-Conflict-of-interest statement.pdf
Copyright License Agreement	50769-Copyright license agreement.pdf
Peer-review Report	50769-Peer-review(s).pdf
Scientific Misconduct Check	50769-Scientific misconduct check.pdf
Scientific Editor Work List	50769-Scientific editor work list.pdf
CrossCheck Report	50769-CrossCheck report.pdf