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2/29/2020 1:53:42 AM | Browse: 150 | Download: 75
Publication Name World Journal of Gastroenterology
Manuscript ID 51726
Country/Territory China
Received
2019-10-03 09:22
Peer-Review Started
2019-10-03 09:22
To Make the First Decision
Return for Revision
2019-11-10 05:28
Revised
2019-12-20 12:44
Second Decision
2020-02-11 11:21
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-02-11 19:34
Articles in Press
2020-02-11 19:34
Publication Fee Transferred
Edit the Manuscript by Language Editor
2020-02-14 08:19
Typeset the Manuscript
2020-02-26 08:13
Publish the Manuscript Online
2020-02-28 03:42
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Basic Study
Article Title Promising key genes associated with tumor microenvironment and prognosis of hepatocellular carcinoma
Manuscript Source Invited Manuscript
All Author List Long Pan, Jing Fang, Ming-Yu Chen, Shu-Ting Zhai, Bin Zhang, Zhi-Yu Jiang, Sarun Juengpanich, Yi-Fan Wang and Xiu-Jun Cai
Funding Agency and Grant Number
Corresponding author Xiu-Jun Cai, FACS, FRCS, MD, PhD, Doctor, Professor, Surgeon, Key Laboratory of Laparoscopic Technique Research of Zhejiang Province, department of General Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, No. 3, Qingchun East Road, Hangzhou 310016, Zhejiang Province, China. srrsh_cxj@zju.edu.cn
Keywords Hepatocellular carcinoma; Tumor microenvironment; Differentially expressed genes; Overall survival; ;
Core Tip We performed an integrated bioinformatics analysis to assess the influence of tumor microenvironment on the prognosis of patients with hepatocellular carcinoma (HCC). The results found that HCC patients with a high immune/stromal infiltration level had better survival benefits than patients with low infiltration level. Ten microenvironment-related key genes were screened and used to construct a prognostic gene signature, presenting good performance in predicting overall survival. Our study provided novel insight into the potential association of tumor microenvironment with HCC prognosis and molecular targeted therapy of HCC in the future.
Publish Date 2020-02-28 03:42
Citation Pan L, Fang J, Chen MY, Zhai ST, Zhang B, Jiang ZY, Juengpanich S, Wang YF, Cai XJ. Promising key genes associated with tumor microenvironment and the prognosis of hepatocellular carcinoma. World J Gastroenterol 2020; 26(8): 789-803
Url https://www.wjgnet.com/1007-9327/full/v26/i8/789.htm
DOI https://dx.doi.org/10.3748/wjg.v26.i8.789
Full Article (PDF) WJG-26-789.pdf
Full Article (Word) WJG-26-789.docx
Manuscript File 51726-Review_WangTQ.docx
Answering Reviewers 51726-Answering reviewers.pdf
Audio Core Tip 51726-Audio core tip.wav
Biostatistics Review Certificate 51726-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 51726-Conflict-of-interest statement.pdf
Copyright License Agreement 51726-Copyright license agreement.pdf
Institutional Review Board Approval Form or Document 51726-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 51726-Language certificate.pdf
Supplementary Material 51726-Supplementary material.pdf
Peer-review Report 51726-Peer-review(s).pdf
Scientific Misconduct Check 51726-Scientific misconduct check.pdf
Scientific Editor Work List 51726-Scientific editor work list.pdf