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2/29/2020 1:52:03 AM | Browse: 67 | Download: 53
Publication Name World Journal of Gastroenterology
Manuscript ID 52713
Country of Manuscript Source Italy
2019-11-25 17:39
Peer-Review Started
2019-11-25 17:39
To Make the First Decision
Return for Revision
2019-12-23 13:41
2020-01-02 12:54
Second Decision
2020-02-07 11:49
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-02-09 16:39
Articles in Press
2020-02-09 16:39
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2020-02-14 02:31
Publish the Manuscript Online
2020-02-21 00:51
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Minireviews
Article Title Proteomic insights on the metabolism in inflammatory bowel disease
Manuscript Source Invited Manuscript
All Author List Laura Francesca Pisani, Manuela Moriggi, Cecilia Gelfi, Maurizio Vecchi and Luca Pastorelli
Funding Agency and Grant Number
Funding Agency Grant Number
Italy’s Ministero Italiano della Salute (Italian Ministry of Health Grant) GR-2016-02364736
Corresponding author Luca Pastorelli, DPhil, MD, Assistant Professor, Doctor, Gastroenterology and Digestive Endoscopy Unit, IRCCS Policlinico San Donato, Piazza Malan, San Donato Milanese 20097, Italy. luca.pastorelli@unimi.it
Keywords Proteomics; Inflammatory bowel disease; Cronh’s disease; Ulcerative colitis; Proteins; Biomarkers discovery
Core Tip Patients' heterogeneity is a hallmark for inflammatory bowel diseases (IBD). Some patients present limited bowel involvement and a mild course of the disease, others develop very extensive, aggressive disease and variable response to therapy. In IBD, there is a great need of patient stratification and of new biomarkers as part of a personalized medicine approach to patient care. Biological therapies are more and more widely used for IBD patients, because of their efficacy in patient’s refractory to other drugs; still, biological treatments fail in 20%-40% of patients and, to date, no reliable clinical or molecular predictor of response to biological therapeutic strategy has been described. This review aims to collect the "omics" approach for research of serological biomarkers of diagnosis, response to specific biological therapies in the IBD field.
Publish Date 2020-02-21 00:51
Citation Pisani LF, Moriggi M, Gelfi C, Vecchi M, Pastorelli L. Proteomic insights on the metabolism in inflammatory bowel disease. World J Gastroenterol 2020; 26(7): 696-705
Url https://www.wjgnet.com/1007-9327/full/v26/i7/696.htm
DOI https://dx.doi.org/10.3748/wjg.v26.i7.696
Full Article (PDF) WJG-26-696.pdf
Full Article (Word) WJG-26-696.docx
Manuscript File 52713-Review.docx
Answering Reviewers 52713-Answering reviewers.pdf
Audio Core Tip 52713-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 52713-Conflict-of-interest statement.pdf
Copyright License Agreement 52713-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 52713-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 52713-Language certificate.pdf
Peer-review Report 52713-Peer-review(s).pdf
Scientific Misconduct Check 52713-Scientific misconduct check.pdf
Scientific Editor Work List 52713-Scientific editor work list.pdf