Publication Name	World Journal of Gastroenterology
Manuscript ID	53913
Country	Italy

Received	2019-12-31 16:48
Peer-Review Started	2019-12-31 16:48
To Make the First Decision
Return for Revision	2020-01-16 20:39
Revised	2020-06-05 22:27
Second Decision	2020-06-18 08:27
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2020-06-18 20:36
Articles in Press	2020-06-18 20:36
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2020-07-06 07:36
Publish the Manuscript Online	2020-07-07 14:50

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Surgery
Manuscript Type	Review
Article Title	Practical review for diagnosis and clinical management of perihilar cholangiocarcinoma
Manuscript Source	Invited Manuscript
All Author List	Daniele Dondossola, Michele Ghidini, Francesco Grossi, Giorgio Rossi and Diego Foschi
Funding Agency and Grant Number
Corresponding Author	Daniele Dondossola, MD, Postdoctoral Fellow, Surgeon, General and Liver Transplant Surgery Unit /Department of Pathophysiology and Transplantation, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico / Università degli Studi of Milan, via F. Sforza, 35, Milan 20122, Italy. dondossola.daniele@gmail.com
Key Words	Perihilar cholangiocarncioma; Perihilar cholangiocarncioma; Biliary drainage; Neo-adjuvant therapy; Type IV cholangiocarcinoma; Klatskin tumor
Core Tip	Perihilar cholangiocarncioma (pCCC) is burdened by a complicated diagnostic iter and its anatomical location makes surgical approach burden by poor results. Confounding factors, such as biliary decompression, must be avoided during diagnosis and evaluation of longitudinal extension of the tumor. While surgical advances allows the extension of surgical indication (especially for type IV pCCC and portal invasion), adjuvant chemotherapy should be administered to improve post-surgical results. Herein, a highlight on diagnostic and therapeutic management is here provided.
Publish Date	2020-07-07 14:50
Citation	Dondossola D, Ghidini M, Grossi F, Rossi G, Foschi D. Practical review for diagnosis and clinical management of perihilar cholangiocarcinoma. World J Gastroentrol 2020; 26(25): 3542-3561
URL	https://www.wjgnet.com/1007-9327/full/v26/i25/3542.htm
DOI	https://dx.doi.org/10.3748/wjg.v26.i25.3542

Full Article (PDF)	WJG-26-3542.pdf
Full Article (Word)	WJG-26-3542.docx
Manuscript File	53913-Review.docx
Answering Reviewers	53913-Answering reviewers.pdf
Audio Core Tip	53913-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	53913-Conflict-of-interest statement.pdf
Copyright License Agreement	53913-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	53913-Language certificate.pdf
Peer-review Report	53913-Peer-review(s).pdf
Scientific Misconduct Check	53913-Scientific misconduct check.pdf
Scientific Editor Work List	53913-Scientific editor work list.pdf
CrossCheck Report	53913-CrossCheck report.pdf