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12/15/2020 9:15:08 AM | Browse: 235 | Download: 672
Publication Name World Journal of Psychiatry
Manuscript ID 54331
Country/Territory China
Received
2020-02-20 21:48
Peer-Review Started
2020-02-20 21:49
To Make the First Decision
Return for Revision
2020-09-21 18:35
Revised
2020-10-06 01:55
Second Decision
2020-11-02 09:51
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-11-05 19:33
Articles in Press
2020-11-05 19:33
Publication Fee Transferred
Edit the Manuscript by Language Editor
2020-11-17 11:41
Typeset the Manuscript
2020-12-07 01:27
Publish the Manuscript Online
2020-12-15 08:41
ISSN 2220-3206 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Psychiatry
Manuscript Type Basic Study
Article Title Identification of key genes involved in post-traumatic stress disorder: Evidence from bioinformatics analysis
Manuscript Source Unsolicited Manuscript
All Author List Yao-Yao Bian, Li-Li Yang, Bin Zhang, Wen Li, Zheng-Jun Li, Wen-Lin Li and Li Zeng
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 81603529
National Natural Science Foundation of China 81704084
National Natural Science Foundation of China 81673982
Natural Science Foundation of the Jiangsu Higher Education Institutions 16KJB360002
Advantages of the Nursing Discipline Project of Jiangsu Province 2019YSHL005
Jiangsu Government Scholarship for Overseas Studies
China Scholarship Council 201908320373
Qing Lan Project 014000773/2018-00376
Corresponding Author Li Zeng, MD, PhD, Academic Research, School of First Clinical Medicine, Nanjing University of Chinese Medicine, No. 138 Xianlin Avenue, Qixia District, Nanjing 210023, Jiangsu Province, China. zengbingli@njucm.edu.cn
Key Words Post-traumatic stress disorder; Differentially expressed genes; Key pathway; Gene-pathway co-expression; Bioinformatics analysis; Microarray
Core Tip Post-traumatic stress disorder (PTSD) is an affective disorder that is exposed by trauma or stress directly or indirectly. The pathogenesis of PTSD is not entirely understood. The purpose of this study is to uncover the critical signatures and key pathways to elucidate the underlying mechanisms of PTSD at the molecular level. To address this issue, the closely related genes and the most enriched pathways were identified by using bioinformatics analysis, which was then validated by using basic study in an exploratory approach. Our results showed that a series of significantly expressed genes and relevant pathways might serve as potential biomarkers involved in the pathogenesis of PTSD.
Publish Date 2020-12-15 08:41
Citation Bian YY, Yang LL, Zhang B, Li W, Li ZJ, Li WL, Zeng L. Identification of key genes involved in post-traumatic stress disorder: Evidence from bioinformatics analysis. World J Psychiatr 2020; 10(12): 286-298
URL https://www.wjgnet.com/2220-3206/full/v10/i12/286.htm
DOI https://dx.doi.org/10.5498/wjp.v10.i12.286
Full Article (PDF) WJP-10-286.pdf
Full Article (Word) WJP-10-286.docx
The ARRIVE Guidelines 54331-The-ARRIVE-Guidelines-revision.pdf
Manuscript File 54331_Auto_Edited_WangTQ.docx
Answering Reviewers 54331-Answering reviewers.pdf
Audio Core Tip 54331-Audio core tip.m4a
Biostatistics Review Certificate 54331-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 54331-Conflict-of-interest statement.pdf
Copyright License Agreement 54331-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 54331-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document 54331-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 54331-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 54331-Language certificate.pdf
Supplementary Material 54331-Supplementary material.pdf
Peer-review Report 54331-Peer-review(s).pdf
Scientific Misconduct Check 54331-Bing-Yan JP-1.png
Scientific Misconduct Check 54331-Bing-Chen XF-2.png
Scientific Misconduct Check 54331-Scientific misconduct check.pdf
Scientific Editor Work List 54331-Scientific editor work list.pdf