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8/24/2020 11:44:15 AM | Browse: 397 | Download: 688
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Received |
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2020-03-09 19:33 |
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Peer-Review Started |
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2020-03-09 19:34 |
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To Make the First Decision |
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Return for Revision |
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2020-04-29 21:46 |
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Revised |
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2020-06-16 18:17 |
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Second Decision |
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2020-07-17 09:34 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2020-07-19 21:58 |
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Articles in Press |
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2020-07-19 21:58 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2020-08-19 01:48 |
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Publish the Manuscript Online |
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2020-08-24 09:59 |
| ISSN |
1949-8470 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Rheumatology |
| Manuscript Type |
Observational Study |
| Article Title |
Quantification of uric acid in vasculature of patients with gout using dual-energy computed tomography
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Sharon Hannah Barazani, Wei-Wei Chi, Renata Pyzik, Helena Chang, Adam Jacobi, Tom O'Donnell, Zahi A Fayad, Yousaf Ali and Venkatesh Mani |
| Funding Agency and Grant Number |
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| Corresponding Author |
Venkatesh Mani, PhD, Associate Professor, Department of Radiology, Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY 10029, United States. venkatesh.mani@mssm.edu |
| Key Words |
Gout; Tophaceous; Dual-energy computed tomography; Hyperuricemia; Monosodium urate; Cardiovascular disease |
| Core Tip |
There is increasing evidence that gout is an independent risk factor for cardiovascular disease progression. In hyperuricemic individuals, monosodium urate may be deposited within the vessel wall and possibly lead to an inflammatory cascade. We examine if dual energy computed tomography can quantify monosodium urate depositions in the vasculature of gout patients, and measure deposits volumetrically to see if they are higher in these individuals compared to healthy controls. The study shows that dual energy computed tomography can detect vascular deposits and that gout patients possibly have increased deposition, and corroborates recent studies that show the presence of vascular deposition. |
| Publish Date |
2020-08-24 09:59 |
| Citation |
Barazani SH, Chi WW, Pyzik R, Chang H, Jacobi M, O’Donnell T, Fayad ZA, Ali Y, Mani V. Quantification of uric acid in vasculature of patients with gout using dual-energy computed tomography. World J Radiol 2020; 12(8): 184-194 |
| URL |
https://www.wjgnet.com/1949-8470/full/v12/i8/184.htm |
| DOI |
https://dx.doi.org/10.4329/wjr.v12.i8.184 |
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