| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Clinicopathological characteristics and surgical outcomes of sarcomatoid hepatocellular carcinoma
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jian-Ping Wang, Zhi-Gang Yao, Ya-Wen Sun, Xi-Han Liu, Feng-Kai Sun, Cun-Hu Lin, Fu-Xin Ren, Bei-Bei Lv, Shuai-Jun Zhang, Yang Wang, Fan-Ying Meng, Shun-Zhen Zheng, Wei Gong and Jun Liu |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81770646 |
| National Natural Science Foundation of China |
81373172 |
| Shandong Provincial Natural Science Foundation, China |
ZR2014HP065 |
| Shandong Provincial Natural Science Foundation, China |
ZR2017BH072 |
| Shandong Key R&D Program |
2015GGB14099 |
| Shandong Key R&D Program |
2017GSF218038 |
|
| Corresponding Author |
Jun Liu, MD, PhD, Chief Doctor, Professor, Surgeon, Surgical Oncologist, Department of Liver Transplantation and Hepatobiliary Surgery, Shandong Provincial Hospital Affiliated to Shandong University, No. 324, Jingwu Road, Jinan 250021, Shandong Province, China. dr_liujun1967@126.com |
| Key Words |
Sarcomatoid hepatocellular carcinoma; Histological composition; Liver resection; Overall survival; Recurrence-free survival; |
| Core Tip |
Sarcomatoid hepatocellular carcinoma is a rare malignancy. Patients usually present with an advanced stage of the disease and have a poor prognosis. Histopathological examination plays an important role in diagnosis because serologic and radiologic examinations cannot help in distinguishing this disease from conventional hepatocellular carcinoma or other intrahepatic masses. Most patients have a history of chronic liver disease; thus, regular ultrasound screening of such patients can help detect tumors at an early stage and reduce the risk of death. Moreover, we discovered that carcinomatous components occupied the predominant proportion of invasions and metastases, and we developed a hypothesis regarding the occurrence of the disease. |
| Publish Date |
2020-08-07 11:36 |
| Citation |
Wang JP, Yao ZG, Sun YW, Liu XH, Sun FK, Lin CH, Ren FX, Lv BB, Zhang SJ, Wang Y, Meng FY, Zheng SZ, Gong W, Liu J. Clinicopathological characteristics and surgical outcomes of sarcomatoid hepatocellular carcinoma. World J Gastroenterol 2020; 26(29): 4327-4342 |
| URL |
https://www.wjgnet.com/1007-9327/full/v26/i29/4327.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v26.i29.4327 |
