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7/29/2020 3:59:38 AM | Browse: 27 | Download: 40
Publication Name World Journal of Gastroenterology
Manuscript ID 55264
Country/Territory China
Received
2020-04-08 13:02
Peer-Review Started
2020-04-08 13:03
To Make the First Decision
Return for Revision
2020-06-13 03:44
Revised
2020-06-25 14:35
Second Decision
2020-07-15 11:52
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-07-16 01:56
Articles in Press
2020-07-16 01:56
Publication Fee Transferred
Edit the Manuscript by Language Editor
2020-07-22 03:33
Typeset the Manuscript
2020-07-28 03:15
Publish the Manuscript Online
2020-07-28 14:46
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Randomized Controlled Trial
Article Title Epigastric pain syndrome: What can traditional Chinese medicine do? A randomized controlled trial of Biling Weitong Granules
Manuscript Source Unsolicited Manuscript
All Author List Yan-Dong Wen, Fang Lu, Ying-Pan Zhao, Ping Wang, Qian Yang, Jun-Xiang Li, Hui-Zhen Li, Li-Li Chi, Zheng-Hua Zhou, Yan-Ping Tang, Jin-Kang Xu, Yang Zhao and Xu-Dong Tang
Funding Agency and Grant Number
Funding Agency Grant Number
National New Drug Innovation Program 2017ZX09304003
Special Research on Modernization of Traditional Chinese Medicine in the National Key Research and Development Program in the 13th Five-Year Plan Demonstrative Research 2017YFC1703703
Corresponding author Xu-Dong Tang, MD, PhD, Chief Doctor, Professor, Department of Gastroenterology, Xiyuan Hospital of China Academy of Chinese Medical Sciences, No. 1 Xiyuancaochang, Haidian District, Beijing 100091, China. txdly@sina.com
Keywords Biling Weitong Granules; Compound formula; Traditional Chinese medicine; Functional dyspepsia; Epigastric pain syndrome; Randomized controlled trial
Core Tip Although the currently available drugs for functional dyspepsia (FD) can, to some extent, improve the symptoms, they are still ineffective or have severe adverse reactions in some patients. The present study evaluated the clinical efficacy and safety of Biling Weitong Granules in treating epigastric pain syndrome in FD patients. Compared with placebo, Biling Weitong Granules markedly relieved the epigastric pain syndrome symptoms and significantly improved the total FD clinical score based on symptoms including postprandial fullness and discomfort, early satiety, epigastric pain, epigastric burning, belching, and pharyngeal obstruction, decreased appetite, fatigue, limb weakness, and irritability, thus, it improved the quality of life without causing serious adverse reactions.
Publish Date 2020-07-28 14:46
Citation Wen YD, Lu F, Zhao YP, Wang P, Yang Q, Li JX, Li HZ, Chi LL, Zhou ZH, Tang YP, Xu JK, Zhao Y, Tang XD. Epigastric pain syndrome: What can traditional Chinese medicine do? A randomized controlled trial of Biling Weitong Granules. World J Gastroenterol 2020; 26(28): 4170-4181
Url https://www.wjgnet.com/1007-9327/full/v26/i28/4170.htm
DOI https://dx.doi.org/10.3748/wjg.v26.i28.4170
Full Article (PDF) WJG-26-4170.pdf
Full Article (Word) WJG-26-4170.docx
Manuscript File 55264-Review-Filipodia.docx
Answering Reviewers 55264-Answering reviewers.pdf
Audio Core Tip 55264-Audio core tip.mp3
Biostatistics Review Certificate 55264-Biostatistics statement.pdf
Clinical Trial Registration Statement 55264-Clinical trial registration statement.pdf
Conflict-of-Interest Disclosure Form 55264-Conflict-of-interest statement.pdf
Copyright License Agreement 55264-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 55264-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 55264-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 55264-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 55264-Language certificate.pdf
Supplementary Material 55264-Supplementary material.pdf
Peer-review Report 55264-Peer-review(s).pdf
Scientific Misconduct Check 55264-Bing-Yan JP-1.png
Scientific Misconduct Check 55264-Scientific misconduct check.pdf
Scientific Editor Work List 55264-Scientific editor work list.pdf