7/29/2020 3:59:38 AM | Browse: 561 | Download: 1280
Publication Name | World Journal of Gastroenterology |
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Manuscript ID | 55264 |
Country | China |
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ISSN | 1007-9327 (print) and 2219-2840 (online) |
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Open Access | This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright | The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints | For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247 |
Permissions | For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207 |
Publisher | Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website | http://www.wjgnet.com |
Category | Gastroenterology & Hepatology | ||||||
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Manuscript Type | Randomized Controlled Trial | ||||||
Article Title | Epigastric pain syndrome: What can traditional Chinese medicine do? A randomized controlled trial of Biling Weitong Granules | ||||||
Manuscript Source | Unsolicited Manuscript | ||||||
All Author List | Yan-Dong Wen, Fang Lu, Ying-Pan Zhao, Ping Wang, Qian Yang, Jun-Xiang Li, Hui-Zhen Li, Li-Li Chi, Zheng-Hua Zhou, Yan-Ping Tang, Jin-Kang Xu, Yang Zhao and Xu-Dong Tang | ||||||
Funding Agency and Grant Number |
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Corresponding Author | Xu-Dong Tang, MD, PhD, Chief Doctor, Professor, Department of Gastroenterology, Xiyuan Hospital of China Academy of Chinese Medical Sciences, No. 1 Xiyuancaochang, Haidian District, Beijing 100091, China. txdly@sina.com | ||||||
Key Words | Biling Weitong Granules; Compound formula; Traditional Chinese medicine; Functional dyspepsia; Epigastric pain syndrome; Randomized controlled trial | ||||||
Core Tip | Although the currently available drugs for functional dyspepsia (FD) can, to some extent, improve the symptoms, they are still ineffective or have severe adverse reactions in some patients. The present study evaluated the clinical efficacy and safety of Biling Weitong Granules in treating epigastric pain syndrome in FD patients. Compared with placebo, Biling Weitong Granules markedly relieved the epigastric pain syndrome symptoms and significantly improved the total FD clinical score based on symptoms including postprandial fullness and discomfort, early satiety, epigastric pain, epigastric burning, belching, and pharyngeal obstruction, decreased appetite, fatigue, limb weakness, and irritability, thus, it improved the quality of life without causing serious adverse reactions. | ||||||
Publish Date | 2020-07-28 14:46 | ||||||
Citation | Wen YD, Lu F, Zhao YP, Wang P, Yang Q, Li JX, Li HZ, Chi LL, Zhou ZH, Tang YP, Xu JK, Zhao Y, Tang XD. Epigastric pain syndrome: What can traditional Chinese medicine do? A randomized controlled trial of Biling Weitong Granules. World J Gastroenterol 2020; 26(28): 4170-4181 | ||||||
URL | https://www.wjgnet.com/1007-9327/full/v26/i28/4170.htm | ||||||
DOI | https://dx.doi.org/10.3748/wjg.v26.i28.4170 |
Full Article (PDF) | WJG-26-4170.pdf |
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Full Article (Word) | WJG-26-4170.docx |
CONSORT 2010 Statement | 55264-CONSORT-2010-Statement-revision.pdf |
Manuscript File | 55264-Review-Filipodia.docx |
Answering Reviewers | 55264-Answering reviewers.pdf |
Audio Core Tip | 55264-Audio core tip.mp3 |
Biostatistics Review Certificate | 55264-Biostatistics statement.pdf |
Clinical Trial Registration Statement | 55264-Clinical trial registration statement.pdf |
Conflict-of-Interest Disclosure Form | 55264-Conflict-of-interest statement.pdf |
Copyright License Agreement | 55264-Copyright license agreement.pdf |
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) | 55264-Grant application form(s).pdf |
Signed Informed Consent Form(s) or Document(s) | 55264-Informed consent statement.pdf |
Institutional Review Board Approval Form or Document | 55264-Institutional review board statement.pdf |
Non-Native Speakers of English Editing Certificate | 55264-Language certificate.pdf |
Supplementary Material | 55264-Supplementary material.pdf |
Peer-review Report | 55264-Peer-review(s).pdf |
Scientific Misconduct Check | 55264-Bing-Yan JP-1.png |
Scientific Misconduct Check | 55264-Scientific misconduct check.pdf |
Scientific Editor Work List | 55264-Scientific editor work list.pdf |
CrossCheck Report | 55264-CrossCheck Report.pdf |