Publication Name	World Journal of Cardiology
Manuscript ID	56379
Country	United States

Received	2020-05-07 17:47
Peer-Review Started	2020-05-07 17:48
To Make the First Decision
Return for Revision	2020-05-24 21:07
Revised	2020-05-31 03:15
Second Decision	2020-09-11 12:25
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2020-09-11 16:33
Articles in Press	2020-09-11 16:33
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2020-10-23 01:02
Publish the Manuscript Online	2020-10-23 08:36

ISSN	1949-8462 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Cardiac & Cardiovascular Systems
Manuscript Type	Meta-Analysis
Article Title	Safety and efficacy of soluble guanylate cyclase stimulators in patients with heart failure: A systematic review and meta-analysis
Manuscript Source	Unsolicited Manuscript
All Author List	Waqas Ullah, Maryam Mukhtar, Aws Al-Mukhtar, Rehan Saeed, Margot Boigon, Donald Haas and Eduardo Rame
Funding Agency and Grant Number
Corresponding Author	Waqas Ullah, MD, Doctor, Department of Internal Medicine, Abington Jefferson Health, 1200 Old York Road, Abington, PA 19001, United States. waqasullah.dr@gmail.com
Key Words	Vericiguat; Riociguat; Soluble guanylate cyclase; Heart failure; Guanylate cyclase stimulator;
Core Tip	Recently soluble guanylate cyclase (sGC) stimulators (vericiguat and riociguat) have emerged as a novel treatment for heart failure with reduced or preserved ejection fraction. Data published in literature revealed no additional benefits to guideline-based medical therapy in reducing incidence of heart failure hospitalization and mortality with sGC stimulator use. Large scale studies are required to determine the efficacy of sGC stimulators in patients with heart failure.
Publish Date	2020-10-23 08:36
Citation	Ullah W, Mukhtar M, Al-Mukhtar A, Saeed R, Boigon M, Haas D, Rame E. Safety and efficacy of soluble guanylate cyclase stimulators in patients with heart failure: A systematic review and meta-analysis. World J Cardiol 2020; 12(10): 501-512
URL	https://www.wjgnet.com/1949-8462/full/v12/i10/501.htm
DOI	https://dx.doi.org/10.4330/wjc.v12.i10.501

Full Article (PDF)	WJC-12-501.pdf
Full Article (Word)	WJC-12-501.docx
Manuscript File	56379-Review.docx
Answering Reviewers	56379-Answering reviewers.pdf
Audio Core Tip	56379-Audio core tip.m4a
Biostatistics Review Certificate	56379-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	56379-Conflict-of-interest statement.pdf
Copyright License Agreement	56379-Copyright license agreement.pdf
Supplementary Material	56379-Supplementary material.pdf
Peer-review Report	56379-Peer-review(s).pdf
Scientific Misconduct Check	56379-Bing-Yan JP-2.png
Scientific Misconduct Check	56379-Scientific misconduct check.pdf
Scientific Editor Work List	56379-Scientific editor work list.pdf