Publication Name	World Journal of Clinical Cases
Manuscript ID	56620
Country	South Korea

Received	2020-05-08 10:43
Peer-Review Started	2020-05-08 10:44
First Decision by Editorial Office Director	2020-05-21 04:18
Return for Revision	2020-05-21 04:18
Revised	2020-06-01 08:00
Publication Fee Transferred
Second Decision by Editor	2020-09-01 12:00
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2020-09-01 19:31
Articles in Press	2020-09-01 19:31
Edit the Manuscript by Language Editor
Typeset the Manuscript	2020-09-24 08:01
Publish the Manuscript Online	2020-09-28 01:45

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Infectious Diseases
Manuscript Type	Retrospective Study
Article Title	Predictive factors for early clinical response in community-onset Escherichia coli urinary tract infection and effects of initial antibiotic treatment on early clinical response
Manuscript Source	Unsolicited Manuscript
All Author List	Young Jun Kim, Jeong-Mi Lee and Jae-Hoon Lee
Funding Agency and Grant Number
Corresponding Author	Jae-Hoon Lee, MD, PhD, Doctor, Doctor, Professor, Department of Internal Medicine and Institute of Wonkwang Medical Science, Wonkwang University College of Medicine, 460, Iksandaero, Iksan 54538, South Korea. john7026@wku.ac.kr
Key Words	Escherichia coli; Urinary tract infections; Adult; Community acquired infections; ;
Core Tip	It is necessary to evaluate the clinical response of patients with urinary tract infections (UTIs) after 72 h of antibiotic therapy as poor clinical response has been related to clinical failure. We performed a single center retrospective study including 511 hospitalized patients (aged ≥ 18 years) who were diagnosed with community-onset Escherichia coli (E. coli) UTI. Among them, 66.1% of the patients had an early clinical response. Patients with an early clinical response had a shorter length of stay (4.3 d) and an earlier defervescence (64 h) than those without an early clinical response. An appropriate initial antibiotic therapy, extended-spectrum β-lactamase-producing E. coli, and a stay in a healthcare facility before admission were factors associated with an early clinical response. However, the initial broad-spectrum antibiotic therapy or initial severe presentations did not impact early clinical response.
Publish Date	2020-09-28 01:45
Citation	Kim YJ, Lee JM, Lee JH. Predictive factors for early clinical response in community-onset Escherichia coli urinary tract infection and effects of initial antibiotic treatment on early clinical response. World J Clin Cases 2020; 8(19): 4342-4348
URL	https://www.wjgnet.com/2307-8960/full/v8/i19/4342.htm
DOI	https://dx.doi.org/10.12998/wjcc.v8.i19.4342

Full Article (PDF)	WJCC-8-4342.pdf
Full Article (Word)	WJCC-8-4342.docx