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10/16/2020 9:28:33 AM | Browse: 605 | Download: 913
Publication Name World Journal of Critical Care Medicine
Manuscript ID 56750
Country/Territory Brazil
Received
2020-06-16 00:10
Peer-Review Started
2020-06-16 00:11
To Make the First Decision
Return for Revision
2020-07-21 16:20
Revised
2020-07-31 00:51
Second Decision
2020-08-24 12:59
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-08-25 05:22
Articles in Press
2020-08-25 05:22
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2020-09-03 01:56
Publish the Manuscript Online
2020-10-16 09:14
ISSN 2220-3141(online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Critical Care Medicine
Manuscript Type Case Control Study
Article Title Association between thrombomodulin and high mobility group box 1 in sepsis patients
Manuscript Source Unsolicited Manuscript
All Author List Adriana Teixeira Rodrigues, Julia Teixeira Rodrigues, Carolina Teixeira Rodrigues, Caroline Maria de Oliveira Volpe, Fabiana Rocha-Silva, Jose Augusto Nogueira-Machado and Luiz Ronaldo Alberti
Funding Agency and Grant Number
Corresponding Author Adriana Teixeira Rodrigues, MD, MSc, Assistant Professor, Attending Doctor, Department of Pediatrics, School of Medicine, Federal University of Minas Gerais, 190, Alfredo Balena Avenue, Belo Horizonte 30130-100, Minas Gerais, Brazil. adrianatr92@gmail.com
Key Words High mobility group box 1; Sepsis; Thrombomodulin; Renal replacement therapy; Mechanical ventilation; Septic shock
Core Tip The knowledge of physiological mechanisms that lead an organism to respond to an infectious agent with such intensity is of great importance. It has been described that during sepsis, an organism produces intense inflammatory activity, caused by the action of several inflammatory mediators. High mobility group box 1 (HMGB1) has been the target of recent studies for its proinflammatory actions as well as for the possibility of having its action reduced by thrombomodulin. For this reason, this study proposed to evaluate the relationship between thrombomodulin and HMGB1 in the initial phase of sepsis and its association with clinical outcomes in sepsis patients.
Publish Date 2020-10-16 09:14
Citation Rodrigues AT, Rodrigues JT, Rodrigues CT, Volpe CMO, Rocha-Silva F, Nogueira-Machado JA, Alberti LR. Association between thrombomodulin and high mobility group box 1 in sepsis patients. World J Crit Care Med 2020; 9(4): 63-73
URL https://www.wjgnet.com/2220-3141/full/v9/i4/63.htm
DOI https://dx.doi.org/10.5492/wjccm.v9.i4.63
Full Article (PDF) WJCCM-9-63.pdf
Full Article (Word) WJCCM-9-63.docx
Manuscript File 56750-Review.docx
Answering Reviewers 56750-Answering reviewers.pdf
Audio Core Tip 56750-Audio core tip.mp3
Biostatistics Review Certificate 56750-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 56750-Conflict-of-interest statement.pdf
Copyright License Agreement 56750-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 56750-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 56750-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 56750-Language certificate.pdf
Peer-review Report 56750-Peer-review(s).pdf
Scientific Misconduct Check 56750-Bing-Huang P-2.png
Scientific Misconduct Check 56750-Bing-Yan JP-1.png
Scientific Misconduct Check 56750-CrossCheck.png
Scientific Misconduct Check 56750-Scientific misconduct check.pdf
Scientific Editor Work List 56750-Scientific editor work list.pdf