Publication Name	World Journal of Gastroenterology
Manuscript ID	56981
Country	Lithuania

Received	2020-05-21 12:00
Peer-Review Started	2020-05-21 12:00
First Decision by Editorial Office Director	2020-05-29 03:09
Return for Revision	2020-05-29 03:09
Revised	2020-06-11 13:57
Publication Fee Transferred
Second Decision by Editor	2020-09-16 12:06
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2020-09-17 04:56
Articles in Press	2020-09-17 04:56
Edit the Manuscript by Language Editor
Typeset the Manuscript	2020-10-14 00:50
Publish the Manuscript Online	2020-10-14 11:33

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Case Control Study
Article Title	Endogenous motion of liver correlates to the severity of portal hypertension
Manuscript Source	Unsolicited Manuscript
All Author List	Sigita Gelman, Andrius Sakalauskas, Romanas Zykus, Andrius Pranculis, Rytis Jurkonis, Irma Kuliavienė, Arūnas Lukoševičius, Limas Kupčinskas and Juozas Kupčinskas
Funding Agency and Grant Number	Funding Agency Grant Number Research Council of Lithuania S-MIP-19-8 Research, Development and Innovation Fund of Kaunas University of Technology MTEPI-L-17003 Research, Development and Innovation Fund of Kaunas University of Technology MTEPI-L-16012
Corresponding Author	Sigita Gelman, MD, PhD, Assistant Lecturer, Attending Doctor, Department of Gastroenterology, Medical Academy, Lithuanian University of Health Sciences, A. Mickeviciaus Str. 9, Kaunas 44307, Lithuania. sigita.gelman@lsmuni.lt
Key Words	Portal hypertension; Endogenous motion; Strain elastography; Hepatic venous pressure gradient; Radiofrequency parameters;
Core Tip	In this study, we aimed to evaluate the feasibility of parameters of endogenously induced displacements and strain of the liver to assess the degree of portal hypertension. Endogenous motion of the liver was characterized by derived parameters of region average tissue displacement signal and results of endogenous tissue strain imaging using specific radiofrequency signal processing algorithm. Our proposed parameters correlated with hepatic venous pressure gradient and statistically significant differences were observed between patient groups with clinically significant and severe portal hypertension. To our knowledge it is the first study to evaluate prognostic potential of endogenous motion parameters to detect clinically significant and severe portal hypertension.
Publish Date	2020-10-14 11:33
Citation	Gelman S, Sakalauskas A, Zykus R, Pranculis A, Jurkonis R, Kuliavienė I, Lukoševičius A, Kupčinskas L, Kupčinskas J. Endogenous motion of liver correlates to the severity of portal hypertension. World J Gastroenterol 2020; 26(38): 5836-5848
URL	https://www.wjgnet.com/1007-9327/full/v26/i38/5836.htm
DOI	https://dx.doi.org/10.3748/wjg.v26.i38.5836

Full Article (PDF)	WJG-26-5836.pdf
Full Article (Word)	WJG-26-5836.docx