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9/4/2020 7:45:03 AM | Browse: 382 | Download: 901
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Received |
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2020-05-29 17:02 |
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Peer-Review Started |
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2020-05-29 17:03 |
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To Make the First Decision |
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Return for Revision |
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2020-06-12 18:08 |
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Revised |
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2020-06-14 13:14 |
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Second Decision |
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2020-07-31 09:47 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-08-01 05:47 |
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Articles in Press |
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2020-08-01 05:47 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2020-08-07 02:01 |
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Typeset the Manuscript |
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2020-08-24 00:53 |
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Publish the Manuscript Online |
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2020-09-04 07:25 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Retrospective Study |
Article Title |
Liver fat accumulation measured by high-speed T2-corrected multi-echo magnetic resonance spectroscopy can predict risk of cholelithiasis
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Hong Chen, Wei-Ke Zeng, Guang-Zi Shi, Ming Gao, Meng-Zhu Wang and Jun Shen |
Funding Agency and Grant Number |
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Corresponding Author |
Jun Shen, MD, Doctor, Doctor, Professor, Department of Radiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107, Yanjiang Road West, Guangzhou 510120, Guangdong Province, China. shenjun@mail.sysu.edu.cn |
Key Words |
Magnetic resonance spectroscopy; Cholelithiasis; Liver fat accumulation; Steatosis; Iron; |
Core Tip |
The increase in total cholesterol synthesis can cause tissues to be overloaded with fatty acids, resulting in more lithogenic bile due to overproduction of hepatic cholesterol. Our study showed that patients with cholelithiasis had higher liver fat content and R2 value as assessed by high speed T2-corrected multi-echo magnetic resonance spectroscopy (MRS). MRS can be used for quantitative detection of mild liver steatosis, and proton density fat fraction (PDFF) derived from MRS can predict the risk of cholelithiasis. PDFF measured by MRS can quantitatively detect liver steatosis in a simple breath-hold of 15 s, which holds a good potential for clinical application. |
Publish Date |
2020-09-04 07:25 |
Citation |
Chen H, Zeng WK, Shi GZ, Gao M, Wang MZ, Shen J. Liver fat accumulation measured by high-speed T2-corrected multi-echo magnetic resonance spectroscopy can predict risk of cholelithiasis. World J Gastroenterol 2020; 26(33): 4996-5007 |
URL |
https://www.wjgnet.com/1007-9327/full/v26/i33/4996.htm |
DOI |
https://dx.doi.org/10.3748/wjg.v26.i33.4996 |
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