BPG is committed to discovery and dissemination of knowledge
Featured Articles
1/6/2021 8:37:19 AM | Browse: 504 | Download: 1068
 |
Received |
|
2020-06-02 14:42 |
|
Peer-Review Started |
|
2020-06-02 14:43 |
 |
To Make the First Decision |
|
|
|
Return for Revision |
|
2020-07-04 21:53 |
|
Revised |
|
2020-11-11 12:48 |
|
Second Decision |
|
2020-11-25 11:45 |
|
Accepted by Journal Editor-in-Chief |
|
|
|
Accepted by Executive Editor-in-Chief |
|
2020-11-29 22:27 |
|
Articles in Press |
|
2020-11-29 22:27 |
|
Publication Fee Transferred |
|
|
|
Edit the Manuscript by Language Editor |
|
2020-12-10 00:51 |
|
Typeset the Manuscript |
|
2020-12-28 00:58 |
|
Publish the Manuscript Online |
|
2021-01-06 07:32 |
| ISSN |
2220-3141(online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Critical Care Medicine |
| Manuscript Type |
Prospective Study |
| Article Title |
Multicentered prospective investigator initiated study to evaluate the clinical outcomes with extracorporeal cytokine adsorption device (cytoSorb®) in patients with sepsis and septic shock
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Rajib Paul, Prachee Sathe, Senthil Kumar, Shiva Prasad, Ma Aleem and Prashant Sakhalvalkar |
| Funding Agency and Grant Number |
|
| Corresponding Author |
Rajib Paul, Visiting Professor, MD, Doctor, Doctor, Professor, Department of Internal Medicine and Critical Care, Apollo Health City, Road Number 72, opp, Bharatiya Vidya Bhavan School, Jubilee Hills, Hyderabad 500033, India. rajib.paulcriticalcare@gmail.com |
| Key Words |
Acute physiology and chronic health evaluation score; Hemadsorption; Sepsis; Sequential organ failure assessment score; Vasopressor |
| Core Tip |
This prospective, real time, observational multicenter study was conducted in 45 patients with sepsis and septic shock. Post therapy, 26 patients survived and dose reduction in norepinephrine, epinephrine and vasopressin was 51.4%, 69.4% and 13.9%, respectively. Interleukin-6 levels reduction was 52.3% and platelet count improved significantly to 30.1%. Mean acute physiology and chronic health evaluation and sequential organ failure assessment scores reduced significantly. Predicted mortality before CytoSorb® therapy was 56.5% that reduced to 48.8% after CytoSorb® therapy. The survival rate in patients given treatment in < 24 h of intensive care unit admission was 75% and 68% when given within 24-48 h of intensive care unit admission. CytoSorb® therapy was safe and well tolerated with no adverse events reported. |
| Publish Date |
2021-01-06 07:32 |
| Citation |
Paul R, Sathe P, Kumar RS, Prasad S, Aleem M, Sakhalvalkar P. Multicentered prospective investigator initiated study to evaluate the clinical outcomes with extracorporeal cytokine adsorption device (cytoSorb®) in patients with sepsis and septic shock. World J Crit Care Med 2021; 10(1): 22-34 |
| URL |
https://www.wjgnet.com/2220-3141/full/v10/i1/22.htm |
| DOI |
https://dx.doi.org/10.5492/wjccm.v10.i1.22 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
