Publication Name	World Journal of Biological Chemistry
Manuscript ID	57318
Country	India

Received	2020-06-04 05:28
Peer-Review Started	2020-06-04 05:28
To Make the First Decision
Return for Revision	2020-07-04 21:50
Revised	2020-07-10 07:14
Second Decision	2020-09-17 13:26
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2020-09-18 20:30
Articles in Press	2020-09-18 20:30
Publication Fee Transferred
Edit the Manuscript by Language Editor	2020-09-24 17:39
Typeset the Manuscript	2020-11-11 03:28
Publish the Manuscript Online	2020-11-11 07:45

ISSN	1949-8454 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Neurosciences
Manuscript Type	Minireviews
Article Title	Deciphering the modifiers for phenotypic variability of X-linked adrenoleukodystrophy
Manuscript Source	Invited Manuscript
All Author List	Shruti V Palakuzhiyil, Rita Christopher and Sadanandavalli Retnaswami Chandra
Funding Agency and Grant Number	Funding Agency Grant Number Department of Biotechnology, New Delhi, India BT/PR26150/MED/12/768/2017
Corresponding Author	Rita Christopher, MD, Professor, Department of Neurochemistry, National Institute of Mental Health and Neuro Sciences, Hosur Road, Bengaluru 560029, India. rita.nimhans@yahoo.com
Key Words	X-adrenoleukodystrophy; Cerebral adrenoleukodystrophy; Adrenomyeloneuropathy; Phenotypic variation; Modifiers;
Core Tip	The monogenic peroxisomal disorder, X-linked adrenoleukodystrophy (X-ALD), presents with different clinical phenotypes. The molecular basis for the phenotypic variation is yet to be resolved and is considered to be influenced by genetic, epigenetic, cellular, or environmental factors. We herein discuss the various modifying factors which can potentially alter the phenotypic presentation of X-ALD.
Publish Date	2020-11-11 07:45
Citation	Palakuzhiyil SV, Christopher R, Chandra SR. Deciphering the modifiers for phenotypic variability of X-linked adrenoleukodystrophy. World J Biol Chem 2020; 11(3): 99-111
URL	https://www.wjgnet.com/1949-8454/full/v11/i3/99.htm
DOI	https://dx.doi.org/10.4331/wjbc.v11.i3.99

Full Article (PDF)	WJBC-11-99.pdf
Full Article (Word)	WJBC-11-99.docx
Manuscript File	57318-Review-Filipodia.docx
Answering Reviewers	57318-Answering reviewers.pdf
Audio Core Tip	57318-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	57318-Conflict-of-interest statement.pdf
Copyright License Agreement	57318-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	57318-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate	57318-Language certificate.pdf
Peer-review Report	57318-Peer-review(s).pdf
Scientific Misconduct Check	57318-Scientific misconduct check.pdf
Scientific Editor Work List	57318-Scientific editor work list.pdf
CrossCheck Report	57318-CrossCheck Report.pdf