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11/26/2020 10:27:57 AM | Browse: 361 | Download: 449
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Received |
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2020-06-21 08:47 |
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Peer-Review Started |
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2020-06-21 08:48 |
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To Make the First Decision |
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Return for Revision |
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2020-08-09 15:08 |
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Revised |
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2020-08-23 09:41 |
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Second Decision |
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2020-09-17 13:40 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2020-09-18 20:22 |
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Articles in Press |
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2020-09-18 20:22 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2020-10-07 03:28 |
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Typeset the Manuscript |
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2020-11-25 06:04 |
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Publish the Manuscript Online |
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2020-11-26 10:14 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Biochemistry & Molecular Biology |
| Manuscript Type |
Review |
| Article Title |
Multifunctional role of microRNAs in mesenchymal stem cell-derived exosomes in treatment of diseases
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hui-Kang Xu, Li-Jun Chen, Si-Ning Zhou, Yi-Fei Li and Charlie Xiang |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Major Scientific and Technological Special Project for “Significant New Drugs Development” of China |
2018ZX09201002-005 |
| National Key R&D Program of China |
2017YFA0105701 |
| National Natural Science Foundation of China |
81900563 |
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| Corresponding Author |
Charlie Xiang, PhD, Director, Professor, The First Affiliated Hospital, zhejiang University school of medicine, 79 Qingchun Road, Hangzhou 310003, China, China. cxiang@zju.edu.cn |
| Key Words |
MicroRNA; Mesenchymal stem cells; Exosomes; Modulation of mesenchymal stem cells; Inflammatory diseases; Injury repair |
| Core Tip |
Mesenchymal stem cell (MSC)-derived exosomes (MSC-exosomes) have obvious therapeutic effects on inflammation, organ damage, and tumors. Exosomes are membranes containing many substances, such as nucleic acids, proteins, and lipids. In many studies, microRNA (miRNA) has been found to be the core substance of therapeutic effect after exosomes are engulfed by cells. MiRNAs in exosomes secreted by different stem cells are diverse. In turn, different miRNAs target different genes to treat matched diseases. This point of view proves that miRNAs in MSC-Exosomes have a broader research space. |
| Publish Date |
2020-11-26 10:14 |
| Citation |
Xu HK, Chen LJ, Zhou SN, Li YF, Xiang C. Multifunctional role of microRNAs in mesenchymal stem cell-derived exosomes in treatment of diseases. World J Stem Cells 2020; 12(11): 1276-1294 |
| URL |
https://www.wjgnet.com/1948-0210/full/v12/i11/1276.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v12.i11.1276 |
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