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11/6/2020 8:26:23 AM | Browse: 305 | Download: 391
Publication Name World Journal of Gastroenterology
Manuscript ID 58438
Country/Territory Greece
Received
2020-07-22 16:16
Peer-Review Started
2020-07-22 16:17
To Make the First Decision
Return for Revision
2020-08-08 16:43
Revised
2020-08-10 08:47
Second Decision
2020-09-24 12:51
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-09-25 05:28
Articles in Press
2020-09-25 05:28
Publication Fee Transferred
Edit the Manuscript by Language Editor
2020-10-10 06:57
Typeset the Manuscript
2020-11-05 01:41
Publish the Manuscript Online
2020-11-06 07:36
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Minireviews
Article Title Origin and genomic characteristics of SARS-CoV-2 and its interaction with angiotensin converting enzyme type 2 receptors, focusing on the gastrointestinal tract
Manuscript Source Invited Manuscript
All Author List Michail Galanopoulos, Aris Doukatas and Maria Gazouli
Funding Agency and Grant Number
Corresponding Author Michail Galanopoulos, FEBG, MD, PhD, Doctor, Department of Gastroenterology, 401 General Military Hospital of Athens, 138 Mesogeion Avenue and Katechaki Street, Athens 11525, Attiki, Greece. galanopoulosdr@gmail.com
Key Words SARS-CoV-2; COVID-19; Gastrointestinal tract; Angiotensin converting enzyme type 2; Angiotensin converting enzyme type 2 receptor; Renin-angiotensin system
Core Tip Although the main route of spread and symptomatology of coronavirus disease 2019 is closely related to respiratory tract, the gastrointestinal tract could be an alternative and potential route of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission and manifestation, most probably as a result of the overexpression of angiotensin converting enzyme type 2 (ACE2) receptors in the digestive system. Thus, this review primarily focuses on the analysis of some critical elements about the SARS-CoV-2 genome and its general characteristics, but most importantly intends to highlight the role of ACE2 receptor in both SARS-CoV-2 replication and pathogenesis, especially in the gastrointestinal tract.
Publish Date 2020-11-06 07:36
Citation Galanopoulos M, Doukatas A, Gazouli M. Origin and genomic characteristics of SARS-CoV-2 and its interaction with angiotensin converting enzyme type 2 receptors, focusing on the gastrointestinal tract. World J Gastroenterol 2020; 26(41): 6335-6345
URL https://www.wjgnet.com/1007-9327/full/v26/i41/6335.htm
DOI https://dx.doi.org/10.3748/wjg.v26.i41.6335
Full Article (PDF) WJG-26-6335.pdf
Full Article (Word) WJG-26-6335.docx
Manuscript File 58438_Auto_Edited-Webster J.docx
Answering Reviewers 58438-Answering reviewers.pdf
Audio Core Tip 58438-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 58438-Conflict-of-interest statement.pdf
Copyright License Agreement 58438-Copyright license agreement.pdf
Peer-review Report 58438-Peer-review(s).pdf
Scientific Misconduct Check 58438-Bing-Yan JP-1.png
Scientific Misconduct Check 58438-Scientific misconduct check.pdf
Scientific Editor Work List 58438-Scientific editor work list.pdf