BPG is committed to discovery and dissemination of knowledge
Featured Articles
2/1/2021 1:37:33 PM | Browse: 731 | Download: 1788
 |
Received |
|
2020-09-27 12:21 |
|
Peer-Review Started |
|
2020-09-27 12:21 |
|
First Decision by Editorial Office Director |
|
2020-12-12 18:36 |
|
Return for Revision |
|
2020-12-12 18:36 |
|
Revised |
|
2020-12-22 11:35 |
 |
Publication Fee Transferred |
|
|
|
Second Decision by Editor |
|
2021-01-05 02:50 |
|
Second Decision by Editor-in-Chief |
|
2021-01-06 04:01 |
|
Final Decision by Editorial Office Director |
|
2021-01-07 20:20 |
|
Articles in Press |
|
2021-01-07 20:20 |
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
2021-01-28 07:10 |
|
Publish the Manuscript Online |
|
2021-02-01 11:01 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Translational Research |
| Article Title |
Total neoadjuvant therapy vs standard therapy of locally advanced rectal cancer with high-risk factors for failure
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Mojca Tuta, Nina Boc, Erik Brecelj, Monika Peternel and Vaneja Velenik |
| Funding Agency and Grant Number |
|
| Corresponding Author |
Vaneja Velenik, MD, PhD, Associate Professor, Division of Radiotherapy, Institute of Oncology, Zaloška cesta 2, Ljubljana 1000, Slovenia. vvelenik@onko-i.si |
| Key Words |
Locally advanced rectal cancer; Total neoadjuvant therapy; Pathological complete response; Neoadjuvant rectal cancer score |
| Core Tip |
Our data suggest that treatment of locally advanced rectal cancer (LARC) with high-risk factors for failure using total neoadjuvant therapy (TNT) is more effective than standard therapy, achieving a higher rate of pathological complete response, more favourable survival prognosis, higher proportion of T-and N-downstaging, shorter time to temporary stoma closure, better compliance, and lower toxicity grade 3-5 during systemic chemotherapy. The outcomes of TNT in patients with the most aggressive form of LARC are completely comparable to TNT in all patients with LARC. |
| Publish Date |
2021-02-01 11:01 |
| Citation |
Tuta M, Boc N, Brecelj E, Peternel M, Velenik V. Total neoadjuvant therapy vs standard therapy of locally advanced rectal cancer with high-risk factors for failure. World J Gastrointest Oncol 2021; 13(2): 119-130
|
| URL |
https://www.wjgnet.com/1948-5204/full/v13/i2/119.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v13.i2.119 |
All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.
