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12/13/2020 5:54:21 AM | Browse: 329 | Download: 611
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Received |
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2020-08-31 11:43 |
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Peer-Review Started |
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2020-08-31 11:44 |
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To Make the First Decision |
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Return for Revision |
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2020-10-05 23:08 |
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Revised |
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2020-10-12 13:57 |
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Second Decision |
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2020-10-26 13:04 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2020-10-26 18:02 |
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Articles in Press |
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2020-10-26 18:02 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2020-11-10 07:16 |
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Typeset the Manuscript |
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2020-12-10 05:24 |
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Publish the Manuscript Online |
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2020-12-13 05:45 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Basic Study |
| Article Title |
Vanadium-dependent activation of glucose transport in adipocytes by catecholamines is not mediated via adrenoceptor stimulation or monoamine oxidase activity
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Jessica Fontaine, Geneviève Tavernier, Nathalie Morin and Christian Carpéné |
| Funding Agency and Grant Number |
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| Corresponding Author |
Christian Carpéné, PhD, Senior Researcher, Institut des Maladies Métaboliques et Cardiovasculaires, Institut National de la Santé et de la Recherche Médicale, INSERM UMR1048, Université Paul Sabatier Toulouse III, CHU Rangueil, Toulouse 31432, France. christian.carpene@inserm.fr |
| Key Words |
Adipocyte; Amine oxidases; Insulin; Diabetes; Vanadium; Obesity |
| Core Tip |
In rat and mouse fat cells, combination of catecholamines with vanadium reproduces the sugar entry activation already reported for benzylamine, methylamine or tyramine. Glucose transport stimulation is observed only with catecholamines at millimolar doses and in the presence of vanadium ineffective on its own. The synergism between adrenaline or noradrenaline and vanadate is not mediated by adrenoceptors and resists to amine oxidase inhibitors; while it is sensitive to antioxidants. Since vanadium exhibits antidiabetic properties, but with toxicological concerns, it is proposed that the combination of catecholamine derivatives plus vanadate salts might generate complexes with safer blood glucose-lowering properties. |
| Publish Date |
2020-12-13 05:45 |
| Citation |
Fontaine J, Tavernier G, Morin N, Carpéné C. Vanadium-dependent activation of glucose transport in adipocytes by catecholamines is not mediated via adrenoceptor stimulation or monoamine oxidase activity. World J Diabetes 2020; 11(12): 622-643 |
| URL |
https://www.wjgnet.com/1948-9358/full/v11/i12/622.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v11.i12.622 |
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