Publication Name	World Journal of Gastroenterology
Manuscript ID	60117
Country	China

Received	2020-10-16 04:59
Peer-Review Started	2020-10-16 05:00
To Make the First Decision
Return for Revision	2020-11-23 05:58
Revised	2020-12-02 14:03
Second Decision	2020-12-09 09:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2020-12-10 20:12
Articles in Press	2020-12-10 20:12
Publication Fee Transferred
Edit the Manuscript by Language Editor	2020-12-21 13:19
Typeset the Manuscript	2020-12-29 14:40
Publish the Manuscript Online	2020-12-30 13:59

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Pediatrics
Manuscript Type	Retrospective Study
Article Title	Searching for the valuable clinical indicators for distinguishing infantile-onset inflammatory bowel disease patients with monogenic diseases
Manuscript Source	Unsolicited Manuscript
All Author List	Wen Su, Yi Yu, Xu Xu, Xin-Qiong Wang, Jie-Bin Huang, Chun-Di Xu and Yuan Xiao
Funding Agency and Grant Number	Funding Agency Grant Number Scientific Research Fund of Shanghai Municipal Health Commission 201640368 National Natural Science Foundation of China Grant 81741103 The Shanghai Plan for Women and Children's Health Service Capacity Construction (Enhancing the Service Capacity of Shanghai Women and Children Health Care Institutions)
Corresponding Author	Yuan Xiao, MD, PhD, Associate Chief Physician, Doctor, Doctor, Department of Pediatrics, Ruijin Hospital, Shanghai Jiao Tong University, School of Medicine, No. 197 Ruijin 2 Road, Shanghai 200025, China. yxiao.penicilinum@gmail.com
Key Words	Infantile-onset inflammatory bowel disease; Immunodeficiency; Clinical indicators; Interleukin 10; Ferritin; IL10RA
Core Tip	It is very important to identify the infantile-onset inflammatory bowel disease (IO-IBD) patients especially those who were caused by monogenic diseases as early as possible because these patients have poor responses to traditional inflammatory bowel disease treatments. However, there are no simple and reliable laboratory indicators for early differential diagnosis. This manuscript was the first study focusing on the laboratory indicators which could be used to distinguish the IO-IBD patients from allergic enteritis patients, as well as screening the IO-IBD patients with monogenic diseases. We believe that these results may be valuable in the initial investigations and diagnosis of IO-IBD.
Publish Date	2020-12-30 13:59
Citation	Su W, Yu Y, Xu X, Wang XQ, Huang JB, Xu CD, Xiao Y. Searching for the valuable clinical indicators for distinguishing infantile-onset inflammatory bowel disease patients with monogenic diseases. World J Gastroenterol 2021; 27(1): 92-106
URL	https://www.wjgnet.com/1007-9327/full/v27/i1/92.htm
DOI	https://dx.doi.org/10.3748/wjg.v27.i1.92

Full Article (PDF)	WJG-27-92.pdf
Full Article (Word)	WJG-27-92.docx
Manuscript File	60117_Auto_Edited_WangTQ.docx
Answering Reviewers	60117-Answering reviewers.pdf
Audio Core Tip	60117-Audio core tip.m4a
Biostatistics Review Certificate	60117-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	60117-Conflict-of-interest statement.pdf
Copyright License Agreement	60117-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	60117-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s)	60117-Informed consent statement.pdf
Institutional Review Board Approval Form or Document	60117-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	60117-Language certificate.pdf
Peer-review Report	60117-Peer-review(s).pdf
Scientific Misconduct Check	60117-Bing-Yan JP-1.png
Scientific Misconduct Check	60117-Scientific misconduct check.pdf
Scientific Editor Work List	60117-Scientific editor work list.pdf
CrossCheck Report	60117-CrossCheck report.pdf