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4/30/2021 6:12:11 AM | Browse: 435 | Download: 839
Publication Name World Journal of Gastrointestinal Pharmacology and Therapeutics
Manuscript ID 60773
Country/Territory Brazil
Received
2020-11-25 20:13
Peer-Review Started
2020-11-25 20:13
To Make the First Decision
Return for Revision
2021-01-07 19:30
Revised
2021-01-20 14:45
Second Decision
2021-04-25 12:26
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-04-25 13:13
Articles in Press
2021-04-25 13:13
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2021-04-29 03:12
Publish the Manuscript Online
2021-04-30 06:05
ISSN 2150-5349 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Systematic Reviews
Article Title Overview of drug induced liver injury in Brazil: What is the role of public health policy on the evidence?
Manuscript Source Invited Manuscript
All Author List Matheus William Becker, Karin Hepp Schwambach, Michele Lunardelli and Carine Raquel Blatt
Funding Agency and Grant Number
Corresponding Author Matheus William Becker, MSc, Pharmacist, Graduate Program in Medicine - Hepatology, Federal University of Health Sciences of Porto Alegre, Sarmento Leite, 245 Street, Porto Alegre 90050-001, RS, Brazil. matheuswbecker@gmail.com
Key Words Chemical and drug-induced liver injury; Pharmacovigilance; Pharmacoepidemiology; Adverse effects; Infectious disease medicine; Hepatotoxicity
Core Tip Hepatotoxicity is the main cause of safety-related drug marketing withdrawals and could be responsible for irreversible and fatal injuries. A systematic review of Brazilian studies was found 32 studies and the hepatotoxicity ranged from one to 57%, lead by isoniazid, rifampicin, and pyrazinamide. Few studies reported algorithm to assess causality and twenty-two different criteria for hepatotoxicity were found. Standardization of parameter of drug-induced liver injury and greater effort in pharmacovigilance could contribute to learn more about DILI's epidemiology in Brazil.
Publish Date 2021-04-30 06:05
Citation Becker MW, Schwambach KH, Lunardelli M, Blatt CR. Overview of drug induced liver injury in Brazil: What is the role of public health policy on the evidence? World J Gastrointest Pharmacol Ther 2021; 12(3): 40-55
URL https://www.wjgnet.com/2150-5349/full/v12/i3/40.htm
DOI https://dx.doi.org/10.4292/wjgpt.v12.i3.40
Full Article (PDF) WJGPT-12-40.pdf
Full Article (Word) WJGPT-12-40.docx
Manuscript File 60773_Auto_Edited-ZMG.docx
Answering Reviewers 60773-Answering reviewers.pdf
Audio Core Tip 60773-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 60773-Conflict-of-interest statement.pdf
Copyright License Agreement 60773-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate 60773-Language certificate.pdf
Peer-review Report 60773-Peer-review(s).pdf
Scientific Misconduct Check 60773-Scientific misconduct check.pdf
Scientific Editor Work List 60773-Scientific editor work list.pdf