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4/2/2021 1:00:03 PM | Browse: 50 | Download: 88
Publication Name World Journal of Clinical Cases
Manuscript ID 61104
Country/Territory China
2020-12-08 12:47
Peer-Review Started
2020-12-08 12:49
To Make the First Decision
Return for Revision
2020-12-30 19:45
2021-01-11 08:18
Second Decision
2021-02-04 08:55
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-02-04 18:25
Articles in Press
2021-02-04 18:25
Publication Fee Transferred
Edit the Manuscript by Language Editor
2021-02-19 23:57
Typeset the Manuscript
2021-03-14 05:17
Publish the Manuscript Online
2021-04-02 12:29
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Medicine, General and Internal
Manuscript Type Case Report
Article Title Biclonal multiple myeloma of immunoglobulin D-λ+λ: A case report
Manuscript Source Unsolicited Manuscript
All Author List Qiao-Ling He, Shuang-Shuang Meng, Jing-Nan Yang, Hui-Chao Wang, Yan-Min Li, Yu-Xia Li and Xu-Hong Lin
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 81500430
National Natural Science Foundation of China U1304802
Science and Technology Planning Project of Henan Province 192102310045
Science and Technology Planning Project of Henan Province 182102310544
Science and Technology Planning Project of Henan Province 182102310566
Science and Technology Planning Project of Henan Province 182102310573
Henan Medical Science and Technology Tackling Project 2018020320
Corresponding Author Xu-Hong Lin, MD, Associate Professor, Department of Clinical Laboratory, Translational Medicine Center, Huaihe Hospital of Henan University, No. 115 Ximen Street, Kaifeng 475000, Henan Province, China. 10220017@vip.henu.edu.cn
Key Words Multiple myeloma; Immunoglobulin D-λ+λ myeloma; Serum protein electrophoresis; Serum immunofixation electrophoresis; Bone marrow histology; Case report
Core Tip Immunoglobulin D (IgD)-λ+λ myeloma are extremely rare and has a later International Staging System stage at diagnosis. The median survival time is shorter than that of other subtypes, and renal insufficiency is prone to occur at the time of diagnosis. Furthermore, the laboratory examination tends to consider IgD-λ+λ myeloma as other isotypes in that its serum immunofixation electrophoresis shows two bands in the λ region but no responding heavy chain band. Therefore, a more complete serum immunofixation electrophoresis should be conducted to reduce the rate of missed diagnoses.
Publish Date 2021-04-02 12:29
Citation He QL, Meng SS, Yang JN, Wang HC, Li YM, Li YX, Lin XH. Biclonal multiple myeloma of immunoglobulin D-λ+λ: A case report. World J Clin Cases 2021; 9(11): 2576-2583
URL https://www.wjgnet.com/2307-8960/full/v9/i11/2576.htm
DOI https://dx.doi.org/10.12998/wjcc.v9.i11.2576
Full Article (PDF) WJCC-9-2576.pdf
Full Article (Word) WJCC-9-2576.docx
Manuscript File 61104_Auto_Edited_LM_WangTQ.docx
Answering Reviewers 61104-Answering reviewers.pdf
Audio Core Tip 61104-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 61104-Conflict-of-interest statement.pdf
Copyright License Agreement 61104-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 61104-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 61104-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate 61104-Language certificate.pdf
Peer-review Report 61104-Peer-review(s).pdf
Scientific Misconduct Check 61104-Scientific misconduct check.pdf
Scientific Editor Work List 61104-Scientific editor work list.pdf