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2/4/2021 1:35:30 PM | Browse: 52 | Download: 69
Publication Name World Journal of Gastrointestinal Surgery
Manuscript ID 61126
Country/Territory Switzerland
Received
2020-11-24 22:08
Peer-Review Started
2020-11-24 22:08
To Make the First Decision
Return for Revision
2020-12-20 03:33
Revised
2021-01-02 20:40
Second Decision
2021-01-12 00:50
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-01-21 20:50
Articles in Press
2021-01-21 20:50
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2021-02-01 05:58
Publish the Manuscript Online
2021-02-04 13:19
ISSN 1948-9366 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Surgery
Manuscript Type Retrospective Cohort Study
Article Title Colorectal cancer of the young displays distinct features of aggressive tumor biology: A single-center cohort study
Manuscript Source Unsolicited Manuscript
All Author List Matteo Mueller, Marcel André Schneider, Barla Deplazes, Daniela Cabalzar-Wondberg, Andreas Rickenbacher and Matthias Turina
Funding Agency and Grant Number
Corresponding Author Matthias Turina, MD, PhD, Professor, Department of Surgery and Transplantation, University Hospital Zurich, Raemistrasse 100, Zurich 8091, Switzerland. matthias.turina@usz.ch
Key Words Young-onset colorectal cancer; Tumor biology; Colorectal surgery; Tumor aggressiveness; Colorectal cancer; Colorectal cancer screening
Core Tip We evaluated differences in tumor biology between young-onset colorectal cancer patients (< 50 years of age) and late-onset colorectal cancer (CRC) patients (≥ 50 years of age) in a Swiss tertiary cancer center over a six-year period. Parameters of interest included clinical as well as histopathological characteristics. This study reports a surprisingly high rate of CRC of young-onset, while affected patients present more frequently with locally advanced tumors, lymphatic invasion and with more frequent lymphatic metastases. This work puts cancer incidence in relation to histopathological details, mutational status, surgical parameters and selected risk factors.
Publish Date 2021-02-04 13:19
Citation Mueller M, Schneider MA, Deplazes B, Cabalzar-Wondberg D, Rickenbacher A, Turina M. Colorectal cancer of the young displays distinct features of aggressive tumor biology: A single-center cohort study. World J Gastrointest Surg 2021; 13(2): 164-175
Url https://www.wjgnet.com/1948-9366/full/v13/i2/164.htm
DOI https://dx.doi.org/10.4240/wjgs.v13.i2.164
Full Article (PDF) WJGS-13-164.pdf
Full Article (Word) WJGS-13-164.docx
Manuscript File 61126_Auto_Edited_LM.docx
Answering Reviewers 61126-Answering reviewers.pdf
Audio Core Tip 61126-Audio core tip.mp3
Biostatistics Review Certificate 61126-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 61126-Conflict-of-interest statement.pdf
Copyright License Agreement 61126-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 61126-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 61126-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 61126-Language certificate.pdf
Peer-review Report 61126-Peer-review(s).pdf
Scientific Misconduct Check 61126-Bing-Wang JL-1.png
Scientific Misconduct Check 61126-Scientific misconduct check.pdf
Scientific Editor Work List 61126-Scientific editor work list.pdf