Publication Name	World Journal of Clinical Cases
Manuscript ID	61155
Country	United States

Received	2020-11-28 14:59
Peer-Review Started	2020-11-29 02:34
To Make the First Decision
Return for Revision	2021-01-24 18:07
Revised	2021-02-03 10:23
Second Decision	2021-03-15 12:50
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2021-03-16 04:24
Articles in Press	2021-03-16 04:24
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-03-21 01:55
Typeset the Manuscript	2021-03-23 01:07
Publish the Manuscript Online	2021-03-26 09:14

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Neurosciences
Manuscript Type	Minireviews
Article Title	Contributions of aversive environmental stress to migraine chronification: Research update of migraine pathophysiology
Manuscript Source	Unsolicited Manuscript
All Author List	Tang-Hua Liu, Zhen Wang, Fang Xie, Yan-Qing Liu and Qing Lin
Funding Agency and Grant Number	Funding Agency Grant Number The Science and Technology Department of Yibin 2016YZY004
Corresponding Author	Qing Lin, PhD, Full Professor, Department of Psychology, University of Texas at Arlington, 501 S. Nedderman Dr., Arlington, TX 76019, United States. qilin@uta.edu
Key Words	Migraine chronification; Aversive environmental stress; Migraine pathophysiology; Migraine headache; Roles of unpleasantness; Emotion brain
Core Tip	In this article, neuronal plasticity for developing migraine chronicity and relevant neurocircuits were reviewed and discussed. Specifically, we focused on providing the most cutting-edge information on neuronal mechanisms involved in the processing of affective aspects of pain and the role of unpleasantness evoked by internal and/or external cues in facilitating the chronification process of migraine headache. New information collected from both preclinical and clinical studies on these aspects may advance our understanding on the chronic migraine pain mechanisms, and lead to new strategies for pain treatment.
Publish Date	2021-03-26 09:14
Citation	Liu TH, Wang Z, Xie F, Liu YQ, Lin Q. Contributions of aversive environmental stress to migraine chronification: Research update of migraine pathophysiology. World J Clin Cases 2021; 9(9): 2136-2145
URL	https://www.wjgnet.com/2307-8960/full/v9/i9/2136.htm
DOI	https://dx.doi.org/10.12998/wjcc.v9.i9.2136

Full Article (PDF)	WJCC-9-2136.pdf
Full Article (Word)	WJCC-9-2136.docx
Manuscript File	61155-Review-FilipodiaCL.docx
Answering Reviewers	61155-Answering reviewers.pdf
Audio Core Tip	61155-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	61155-Conflict-of-interest statement.pdf
Copyright License Agreement	61155-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	61155-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate	61155-Language certificate.pdf
Peer-review Report	61155-Peer-review(s).pdf
Scientific Misconduct Check	61155-Scientific misconduct check.pdf
Scientific Editor Work List	61155-Scientific editor work list.pdf
CrossCheck Report	61155-CrossCheck report.pdf