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4/9/2021 5:45:04 AM | Browse: 322 | Download: 623
Publication Name World Journal of Diabetes
Manuscript ID 61498
Country/Territory China
Received
2020-12-12 03:23
Peer-Review Started
2020-12-11 02:28
To Make the First Decision
Return for Revision
2021-01-11 02:01
Revised
2021-01-12 02:07
Second Decision
2021-02-03 09:55
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-03-08 05:03
Articles in Press
2021-03-08 05:03
Publication Fee Transferred
Edit the Manuscript by Language Editor
2021-03-15 17:10
Typeset the Manuscript
2021-03-22 03:13
Publish the Manuscript Online
2021-04-09 05:27
ISSN 1948-9358 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Radiology, Nuclear Medicine & Medical Imaging
Manuscript Type Basic Study
Article Title Three-dimensional-arterial spin labeling perfusion correlation with diabetes-associated cognitive dysfunction and vascular endothelial growth factor in type 2 diabetes mellitus rat
Manuscript Source Unsolicited Manuscript
All Author List Ju-Wei Shao, Jin-De Wang, Qian He, Ying Yang, Ying-Ying Zou, Wei Su, Shu-Tian Xiang, Jian-Bo Li and Jing Fang
Funding Agency and Grant Number
Funding Agency Grant Number
Endocrine Clinical Medical Center of Yunnan Province ZX2019‑02‑02
Fund of the Diabetic Innovation Team in Yunnan Province 2019HC002
Special Joint Fund from Yunnan Provincial Department of Science and Technology and Kunming Medical University, Kunming, Yunnan, China. 2018FE001(-267)
SKY Image Research Fund China Z-2014-07-2003-12
Corresponding Author Jing Fang, MD, Professor, Institute for Health Sciences, Kunming Medical University, No. 1168 Chunrong West Road, Yuhua Street, Chenggong District, Kunming 650500, Yunnan , China. fangjing07@126.com
Key Words Diabetes-associated cognitive dysfunction; Diabetes mellitus; Type 2; Perfusion imaging; Receptors; Vascular endothelial growth factor; Hippocampus; Three-dimensional pseudo-continuous arterial spin labeling
Core Tip This study aimed to assess the correlation between cerebral blood flow (CBF) measured by 3D arterial spin labeling (3D-ASL), vascular endothelial growth factor (VEGF) expression, and diabetes-associated cognitive dysfunction (DACD) in a rat model of type 2 diabetes (T2DM). Our result showed low CBF in the hippocampus and decreased VEGF expression might be crucial in DACD. CBF measured on 3D-ASL might serve as a noninvasive imaging biomarker for cognitive impairment associated with T2DM. This study would help in the early detection of DACD and guide treatment.
Publish Date 2021-04-09 05:27
Citation Shao JW, Wang JD, He Q, Yang Y, Zou YY, Su W, Xiang ST, Li JB, Fang J. Three-dimensional-arterial spin labeling perfusion correlation with diabetes-associated cognitive dysfunction and vascular endothelial growth factor in type 2 diabetes mellitus rat. World J Diabetes 2021; 12(4): 499-513
URL https://www.wjgnet.com/1948-9358/full/v12/i4/499.htm
DOI https://dx.doi.org/10.4239/wjd.v12.i4.499
Full Article (PDF) WJD-12-499.pdf
Full Article (Word) WJD-12-499.docx
Manuscript File 61498-Review-FilipodiaCL.docx
Answering Reviewers 61498-Answering reviewers.pdf
Audio Core Tip 61498-Audio core tip.m4a
Biostatistics Review Certificate 61498-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 61498-Conflict-of-interest statement.pdf
Copyright License Agreement 61498-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 61498-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document 61498-Institutional animal care and use committee statement.pdf
Non-Native Speakers of English Editing Certificate 61498-Language certificate.pdf
Peer-review Report 61498-Peer-review(s).pdf
Scientific Misconduct Check 61498-Scientific misconduct check.pdf
Scientific Editor Work List 61498-Scientific editor work list.pdf