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3/18/2021 10:44:19 AM | Browse: 486 | Download: 474
Publication Name World Journal of Gastrointestinal Surgery
Manuscript ID 61568
Country/Territory United Kingdom
Received
2020-12-11 14:49
Peer-Review Started
2020-12-11 14:50
To Make the First Decision
Return for Revision
2021-01-11 04:04
Revised
2021-01-17 08:20
Second Decision
2021-02-20 06:41
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-03-03 02:50
Articles in Press
2021-03-03 02:50
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2021-03-17 02:07
Publish the Manuscript Online
2021-03-18 09:01
ISSN 1948-9366 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Endocrinology & Metabolism
Manuscript Type Review
Article Title Gastroenteropancreatic neuroendocrine neoplasms: A clinical snapshot
Manuscript Source Invited Manuscript
All Author List Cornelius J Fernandez, Mayuri Agarwal, Biju Pottakkat, Nisha Nigil Haroon, Annu Susan George and Joseph M Pappachan
Funding Agency and Grant Number
Corresponding Author Joseph M Pappachan, FRCP (Hon), MD, MRCP, Consultant Physician-Scientist, Senior Researcher, Department of Endocrinology and Metabolism, Lancashire Teaching Hospitals NHS Trust, The University of Manchester and Manchester Metropolitan University, All Saints Building M15 6BH, Oxford Road M13 9PL, Preston and Manchester PR2 9HT, United Kingdom. drpappachan@yahoo.co.in
Key Words Gastroenteropancreatic neuroendocrine neoplasms; Neuroendocrine tumours; Neuroendocrine carcinoma; Targeted molecular therapy; Octreoscan; Chemotherapy
Core Tip Gut, the largest endocrine organ of the body, secretes several hormones through its specialised neuroendocrine cells. Neuroendocrine neoplasms (NENs) originating from these cells are collectively known as gastroenteropancreatic (GEP) NENs that pose significant challenges to clinicians in the diagnostic work up, prognostication and management. Rapid advancements in the molecular diagnostic and therapeutic strategies in the recent years revolutionised the options for clinical investigations and management of patients with these uncommon neoplasms. This review updates the pathophysiological aspects, diagnostic strategies, and management algorithms of GEP NENs with the best evidence currently available in the global scientific literature to enable clinicians to optimally manage these unusual disease entities.
Publish Date 2021-03-18 09:01
Citation Fernandez CJ, Agarwal M, Pottakkat B, Haroon NN, George AS, Pappachan JM. Gastroenteropancreatic neuroendocrine neoplasms: A clinical snapshot. World J Gastrointest Surg 2021; 13(3): 231-255
URL https://www.wjgnet.com/1948-9366/full/v13/i3/231.htm
DOI https://dx.doi.org/10.4240/wjgs.v13.i3.231
Full Article (PDF) WJGS-13-231.pdf
Full Article (Word) WJGS-13-231.docx
Manuscript File 61568_Auto_Edited_LM.docx
Answering Reviewers 61568-Answering reviewers.pdf
Audio Core Tip 61568-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 61568-Conflict-of-interest statement.pdf
Copyright License Agreement 61568-Copyright license agreement.pdf
Peer-review Report 61568-Peer-review(s).pdf
Scientific Misconduct Check 61568-Bing-Ma YJ-1.jpg
Scientific Misconduct Check 61568-Bing-Fan JR-2.png
Scientific Misconduct Check 61568-Scientific misconduct check.pdf
Scientific Editor Work List 61568-Scientific editor work list.pdf