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3/11/2021 9:28:12 AM | Browse: 252 | Download: 424
Publication Name World Journal of Gastroenterology
Manuscript ID 61586
Country/Territory Spain
Received
2020-12-12 17:14
Peer-Review Started
2020-12-12 17:18
To Make the First Decision
Return for Revision
2020-12-27 20:40
Revised
2021-01-03 09:48
Second Decision
2021-02-08 08:33
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-02-11 17:42
Articles in Press
2021-02-11 17:42
Publication Fee Transferred
Edit the Manuscript by Language Editor
2021-02-24 07:58
Typeset the Manuscript
2021-03-09 08:05
Publish the Manuscript Online
2021-03-11 08:31
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Opinion Review
Article Title Use of granulocyte/monocytapheresis in ulcerative colitis: A practical review from a European perspective
Manuscript Source Unsolicited Manuscript
All Author List Eugeni Domènech, Joan-Ramon Grífols, Ayesha Akbar and Axel U Dignass
Funding Agency and Grant Number
Corresponding Author Eugeni Domènech, MD, PhD, Chief Physician, Professor, Department of Gastroenterology, Hospital Universitari Germans Trias i Pujol, Carretera del Canyet s/n, Badalona 08916, Catalonia, Spain. eugenidomenech@gmail.com
Key Words Granulocyte; Monocyte; Ulcerative colitis; Inflammatory bowel disease; Apheresis; Safety
Core Tip About 30%-40% of patients with ulcerative colitis will require immunosuppressive therapies, including immunomodulators and biological agents. Unfortunately, none of these therapies achieves more than 40% of steroid-free clinical remission in the middle term; moreover, most immunosuppressive therapies increase the risk of infections and some malignancies, raising the unmet need for therapeutic alternatives in ulcerative colitis. Granulocyte/monocytapheresis (GMA) remains the only therapy targeting neutrophils, the hallmark of pathology in ulcerative colitis. GMA has proven its efficacy in different clinical scenarios and shows an excellent and unique safety profile.
Publish Date 2021-03-11 08:31
Citation Domènech E, Grífols JR, Akbar A, Dignass AU. Use of granulocyte/monocytapheresis in ulcerative colitis: A practical review from a European perspective. World J Gastroenterol 2021; 27(10): 908-918
URL https://www.wjgnet.com/1007-9327/full/v27/i10/908.htm
DOI https://dx.doi.org/10.3748/wjg.v27.i10.908
Full Article (PDF) WJG-27-908.pdf
Full Article (Word) WJG-27-908.docx
Manuscript File 61586_Auto_Edited_LM-Webster J-Clear.docx
Answering Reviewers 61586-Answering reviewers.pdf
Audio Core Tip 61586-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 61586-Conflict-of-interest statement.pdf
Copyright License Agreement 61586-Copyright license agreement.pdf
Peer-review Report 61586-Peer-review(s).pdf
Scientific Misconduct Check 61586-Bing-Wang JL-1.jpg
Scientific Misconduct Check 61586-Scientific misconduct check.pdf
Scientific Editor Work List 61586-Scientific editor work list.pdf