| ISSN |
2220-3249 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Infectious Diseases |
| Manuscript Type |
Review |
| Article Title |
Bottom-up analysis of emergent properties of N-acetylcysteine as an adjuvant therapy for COVID-19
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Asimina Dominari, Donald Hathaway III, Abdulhusein Kapasi, Trissa Paul, Sarabjot Singh Makkar, Valeria Castaneda, Sirisha Gara, Bishnu Mohan Singh, Kuchalambal Agadi, Maliha Butt, Varadha Retnakumar, Spandana Chittajallu, Rahima Taugir, Muhammad Khawar Sana, Manish KC, Sarah Razzack, Niala Moallem, Alina Alvarez and Michael Talalaev |
| Funding Agency and Grant Number |
|
| Corresponding Author |
Donald Hathaway III, MD, Division of Research and Academic Affairs, Larkin Health System, 7031 SW 62nd Avenue, South Miami, FL 33143, United States. donald.hathaway@larkinhospital.com |
| Key Words |
N-acetylcysteine; Antioxidant; COVID-19; SARS-CoV-2; Treatment |
| Core Tip |
N-acetylcysteine is a long known antioxidant that is currently best studied for its use as an antidote for acetaminophen overdose. Its off-label use in various diseases, such as chronic respiratory disease, heart disease, cancer, human immunodeficiency virus infection, and seasonal influenza, has shown promising results, as have recent clinical trials investigating the potential benefits of N-acetylcysteine in patients with coronavirus disease 2019. |
| Publish Date |
2021-03-16 09:17 |
| Citation |
Dominari A, Hathaway III D, Kapasi A, Paul T, Makkar SS, Castaneda V, Gara S, Singh BM, Agadi K, Butt M, Retnakumar V, Chittajallu S, Taugir R, Sana MK, KC M, Razzack S, Moallem N, Alvarez A, Talalaev M. Bottom-up analysis of emergent properties of n-acetylcysteine as an adjuvant therapy for COVID-19. World J Virol 2021; 10(2): 34-52 |
| URL |
https://www.wjgnet.com/2220-3249/full/v10/i2/34.htm |
| DOI |
https://dx.doi.org/10.5501/wjv.v10.i2.34 |
