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5/18/2021 11:28:43 AM | Browse: 426 | Download: 1341
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Received |
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2021-01-10 22:12 |
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Peer-Review Started |
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2021-01-10 22:13 |
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First Decision by Editorial Office Director |
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2021-02-15 03:37 |
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2021-02-15 03:37 |
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Revised |
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2021-02-21 01:35 |
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Second Decision by Editor |
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2021-04-07 12:44 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2021-04-07 17:21 |
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Articles in Press |
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2021-04-07 17:21 |
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Edit the Manuscript by Language Editor |
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2021-04-15 18:54 |
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Typeset the Manuscript |
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2021-04-29 07:21 |
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Publish the Manuscript Online |
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2021-05-18 11:27 |
| ISSN |
2220-3249 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Evidence-Based Medicine |
| Article Title |
Association between population vitamin D status and SARS-CoV-2 related serious-critical illness and deaths: An ecological integrative approach
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Dimitrios T Papadimitriou, Alexandros K Vassaras and Michael F Holick |
| Funding Agency and Grant Number |
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| Corresponding Author |
Dimitrios T Papadimitriou, MD, MSc, PhD, Director, Director, Pediatric - Adolescent Endocrinology & Diabetes, Athens Medical Center, 58, Kifisias av., Marousi 15125, Greece. info@pedoendo.net |
| Key Words |
COVID-19; SARS-CoV-2; Vitamin D status; Vitamin D concentrations; 25-hydroxyvitamin-D; Immunity |
| Core Tip |
To elucidate the role of vitamin D in the coronavirus disease 2019 (COVID-19) pandemic, we examined associations between published representative and standardized European population vitamin D data and the Worldometer COVID-19 data. Linear regression found no correlation between population vitamin D concentrations and the total cases-recovered/million (M), but negative correlations predicting a reduction of 47%-64%-80% in serious-critical illnesses/M and of 61%-82%-102.4% in deaths/M, further enhanced when adapting for life expectancy by 133-177-221% if 25-hydroxyvitamin-D concentrations reach 100-125-150 nmol/L. Weighted ANOVA/ANCOVA showed a decreasing trend (P < 0.001) evaluating serious-critical/M (r2 = 0.22), and the deaths/M (r2 = 0.629) after controlling for life expectancy (r2 = 0.47), by vitamin D population status, respectively. |
| Publish Date |
2021-05-18 11:27 |
| Citation |
Papadimitriou DT, Vassaras AK, Holick MF. Association between population vitamin D status and SARS-CoV-2 related serious-critical illness and deaths: An ecological integrative approach. World J Virol 2021; 10(3): 111-129 |
| URL |
https://www.wjgnet.com/2220-3249/full/v10/i3/111.htm |
| DOI |
https://dx.doi.org/10.5501/wjv.v10.i3.111 |
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