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7/19/2021 2:13:13 PM | Browse: 24 | Download: 36
Publication Name World Journal of Gastroenterology
Manuscript ID 62595
Country/Territory South Korea
Received
2021-02-21 02:05
Peer-Review Started
2021-02-21 02:08
To Make the First Decision
Return for Revision
2021-05-13 00:36
Revised
2021-05-16 22:33
Second Decision
2021-07-07 12:57
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-07-07 13:53
Articles in Press
2021-07-07 13:53
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2021-07-15 06:44
Publish the Manuscript Online
2021-07-19 14:10
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Observational Study
Article Title Prognostic role of plasma level of angiopoietin-1, angiopoitin-2, and vascular endothelial growth factor in hepatocellular carcinoma
Manuscript Source Unsolicited Manuscript
All Author List Gwang Hyeon Choi, Eun Sun Jang, Jin-Wook Kim and Sook‐Hyang Jeong
Funding Agency and Grant Number
Funding Agency Grant Number
Seoul National University Bundang Hospital Research Fund 02-2019-037
Corresponding Author Sook‐Hyang Jeong, PhD, Professor, Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, 82 Gumi-ro 173 beon-gil, Bundang-gu, Seongnam-si, Gyeonggi-do, Seongnam 13620, South Korea. jsh@snubh.org
Key Words Hepatocellular carcinoma; Angiogenesis; Biomarker; Prognosis; Survival
Core Tip Most hepatocellular carcinomas (HCCs) are hypervascular tumor, thus angiogenesis markers can be a potential biomarker. This study explored the potential of each plasma level of angiopoietin (Ang)-1, Ang-2, and vascular endothelial growth factor as a prognostic biomarker for very early to advanced stages of HCC via detailed analysis in comparison with alpha-fetoprotein. The plasma level of Ang-2 correlated with liver function, tumor stage, and tumor invasiveness. Multivariable and propensity score-matched analyses revealed Ang-2 levels with the highest predictive power for overall survival in patients with HCC.
Publish Date 2021-07-19 14:10
Citation Choi GH, Jang ES, Kim JW, Jeong SH. Prognostic role of plasma level of angiopoietin-1, angiopoitin-2, and vascular endothelial growth factor in hepatocellular carcinoma. World J Gastroenterol 2021; 27(27): 4453-4467
URL https://www.wjgnet.com/1007-9327/full/v27/i27/4453.htm
DOI https://dx.doi.org/10.3748/wjg.v27.i27.4453
Full Article (PDF) WJG-27-4453.pdf
Full Article (Word) WJG-27-4453.docx
Manuscript File 62595_Auto_Edited-ZMG.docx
Answering Reviewers 62595-Answering reviewers.pdf
Audio Core Tip 62595-Audio core tip.m4a
Biostatistics Review Certificate 62595-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 62595-Conflict-of-interest statement.pdf
Copyright License Agreement 62595-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 62595-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 62595-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 62595-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 62595-Language certificate.pdf
Supplementary Material 62595-Supplementary material.pdf
Peer-review Report 62595-Peer-review(s).pdf
Scientific Misconduct Check 62595-Bing-Wang JL-1.jpg
Scientific Misconduct Check 62595-Bing-Fan JR-2.png
Scientific Misconduct Check 62595-Scientific misconduct check.pdf
Scientific Editor Work List 62595-Scientific editor work list.pdf