Publication Name	World Journal of Gastroenterology
Manuscript ID	62780
Country	Pakistan

Received	2021-01-18 10:04
Peer-Review Started	2021-01-18 10:06
To Make the First Decision
Return for Revision	2021-02-09 21:07
Revised	2021-02-17 07:03
Second Decision	2021-03-19 11:21
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-03-19 14:51
Articles in Press	2021-03-19 14:51
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-03-23 14:35
Typeset the Manuscript	2021-03-26 07:55
Publish the Manuscript Online	2021-03-30 07:03

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	COVID-19 and co-morbidities of hepatic diseases in a global perspective
Manuscript Source	Invited Manuscript
All Author List	Aqsa Ahmad, Syeda Momna Ishtiaq, Junaid Ali Khan, Rizwan Aslam, Sultan Ali and Muhammad Imran Arshad
Funding Agency and Grant Number
Corresponding Author	Muhammad Imran Arshad, PhD, Assistant Professor, Institute of Microbiology, University of Agriculture Faisalabad, Main Agriculture University and Jail Road, Faisalabad 38040, Punjab, Pakistan. drimranarshad@yahoo.com
Key Words	Liver diseases; COVID-19; Pathophysiology; Epidemiology; Prophylaxis
Core Tip	The clinical menace of coronavirus disease 2019 (COVID-19)-related co-morbidities of hepatic diseases and severe acute respiratory syndrome-coronavirus type 2 (SARS-CoV-2) tropism for liver have resulted in liver impairment with increased liver injury markers and cytokine storm. The SARS-CoV-2 aggravates liver injury via coagulative and fibrinolytic pathways, cytokine mediated liver injury, ischemia-hypoxia and immune mediated cell death pathways owing to adverse outcome of liver diseases such as non-alcoholic steatohepatitis, drug-induced liver injuries, non-alcoholic fatty liver disease, metabolic associated fatty liver disease and hepatocellular carcinoma. This review presented diagnostic approaches, therapeutics, clinical guidelines and vaccines for COVID-19 and co-morbidities of liver diseases.
Publish Date	2021-03-30 07:03
Citation	Ahmad A, Ishtiaq SM, Khan JA, Aslam R, Ali S, Arshad MI. COVID-19 and co-morbidities of hepatic diseases in a global perspective. World J Gastroenterol 2021; 27(13): 1296-1310
URL	https://www.wjgnet.com/1007-9327/full/v27/i13/1296.htm
DOI	https://dx.doi.org/10.3748/wjg.v27.i13.1296

Full Article (PDF)	WJG-27-1296.pdf
Full Article (Word)	WJG-27-1296.docx
Manuscript File	62780-Review-FilipodiaCL.docx
Answering Reviewers	62780-Answering reviewers.pdf
Audio Core Tip	62780-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	62780-Conflict-of-interest statement.pdf
Copyright License Agreement	62780-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	62780-Language certificate.pdf
Peer-review Report	62780-Peer-review(s).pdf
Scientific Misconduct Check	62780-Scientific misconduct check.pdf
Scientific Editor Work List	62780-Scientific editor work list.pdf