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3/30/2021 7:06:58 AM | Browse: 46 | Download: 77
Publication Name World Journal of Gastroenterology
Manuscript ID 63044
Country/Territory United Kingdom
2021-01-23 13:34
Peer-Review Started
2021-01-23 13:39
To Make the First Decision
Return for Revision
2021-02-10 05:40
2021-02-10 12:53
Second Decision
2021-03-11 13:23
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-03-12 00:41
Articles in Press
2021-03-12 00:41
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2021-03-22 03:24
Publish the Manuscript Online
2021-03-30 07:03
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Endocrinology and Metabolism
Manuscript Type Review
Article Title Metabolic complications of hepatitis C virus infection
Manuscript Source Invited Manuscript
All Author List Rahul Chaudhari, Sherouk Fouda, Ashik Sainu and Joseph M Pappachan
Funding Agency and Grant Number
Corresponding Author Joseph M Pappachan, FRCP, MD, Consultant Physician-Scientist, Honorary Research Fellow, Senior Researcher, Department of Endocrinology and Metabolism , Lancashire Teaching Hospitals NHS Trust, Royal Preston Hospital, Preston PR2 9HT, United Kingdom. drpappachan@yahoo.co.in
Key Words Chronic hepatitis C infection; Insulin resistance; Metabolic syndrome; Cardiovascular diseases; Fatty liver; Diabetes mellitus
Core Tip Available evidence proves a strong association between hepatitis C virus (HCV) and metabolic complications such as hyperlipidemia, hepatic steatosis, insulin resistance, metabolic syndrome, and diabetes mellitus. De novo development of insulin resistance and hepatic steatosis in chronic HCV infection influences the disease progression in the liver and enhances overall morbidity and mortality. The influence of metabolic diseases on HCV infection can increase disease severity. The interplay between HCV major proteins and the liver-muscle-adipose axis is complex and still not fully elucidated. Coexistence of metabolic diseases such as diabetes mellitus and HCV infection are also known to result in adverse outcomes of both disorders. There is evidence that successful treatment halts the progression of liver disease, but more studies are required on how treatment influences the metabolic manifestations.
Publish Date 2021-03-30 07:03
Citation Chaudhari R, Fouda S, Sainu A, Pappachan JM. Metabolic complications of hepatitis C virus infection. World J Gastroenterol 2021; 27(13): 1267-1282
URL https://www.wjgnet.com/1007-9327/full/v27/i13/1267.htm
DOI https://dx.doi.org/10.3748/wjg.v27.i13.1267
Full Article (PDF) WJG-27-1267.pdf
Full Article (Word) WJG-27-1267.docx
Manuscript File 63044_Auto_Edited.docx
Answering Reviewers 63044-Answering reviewers.pdf
Audio Core Tip 63044-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 63044-Conflict-of-interest statement.pdf
Copyright License Agreement 63044-Copyright license agreement.pdf
Peer-review Report 63044-Peer-review(s).pdf
Scientific Misconduct Check 63044-Bing-Wang JL-1.jpg
Scientific Misconduct Check 63044-Scientific misconduct check.pdf
Scientific Editor Work List 63044-Scientific editor work list.pdf