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10/15/2021 9:59:38 AM | Browse: 185 | Download: 264
Publication Name World Journal of Clinical Cases
Manuscript ID 63549
Country/Territory United States
Received
2021-01-29 04:38
Peer-Review Started
2021-01-29 04:43
To Make the First Decision
Return for Revision
2021-05-04 09:07
Revised
2021-05-20 00:44
Second Decision
2021-09-08 03:00
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-09-08 10:30
Articles in Press
2021-09-08 10:30
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2021-10-11 08:00
Publish the Manuscript Online
2021-10-15 09:45
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Observational Study
Article Title Chronic hepatitis-C infection in COVID-19 patients is associated with in-hospital mortality
Manuscript Source Unsolicited Manuscript
All Author List Diana Ronderos, Alaa Mabrouk Salem Omar, Hafsa Abbas, Jasbir Makker, Ahmed Baiomi, Haozhe Sun, Nikhitha Mantri, YongsuN Choi, Ked Fortuzi, Dongmin Shin, Harish Patel and Sridhar Chilimuri
Funding Agency and Grant Number
Corresponding Author Sridhar Chilimuri, MD, Chairman, Department of Internal Medicine, BronxCare Hospital Center, 1650 Grand Concourse, Bronx, NY 10457, United States. chilimuri@bronxcare.org
Key Words Hepatitis C; Acute liver injury; Seropositive; COVID-19; Mortality
Core Tip In patients with coronavirus disease 2019 (COVID-19), history of hepatitis C infection accentuated severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) viral virulence and is a strong predictor of in-hospital mortality irrespective of baseline comorbidities, laboratory parameters, or COVID-19-induced liver injury. History of hepatitis C infection (HCV) in these patients seems to add a cumulative mortality risk to any clinical or laboratory profile. The mechanisms involved may be related to extra hepatic effects of HCV leading to enhanced ACE-2/TMPRSS mechanisms of SARS-CoV-2 virus and subsequent endothelial dysfunction. The realization is important for better characterization of the disease and triage this sub-group as high risk for therapeutic or prophylactic measures like vaccines.
Publish Date 2021-10-15 09:45
Citation Ronderos D, Omar AMS, Abbas H, Makker J, Baiomi A, Sun H, Mantri N, Choi Y, Fortuzi K, Shin D, Patel H, Chilimuri S. Chronic and Seropositive Hepatitis C Infection in COVID-19 patients is Associated with In-Hospital Mortality Independent of Baseline Comorbidities and Liver Injury. World J Clin Cases 2021; 9(29): 8749-8762
URL https://www.wjgnet.com/2307-8960/full/v9/i29/8749.htm
DOI https://dx.doi.org/10.12998/wjcc.v9.i29.8749
Full Article (PDF) WJCC-9-8749.pdf
Full Article (Word) WJCC-9-8749.docx
Manuscript File 63549_Auto_Edited.docx
Answering Reviewers 63549-Answering reviewers.pdf
Audio Core Tip 63549-Audio core tip.mp3
Biostatistics Review Certificate 63549-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 63549-Conflict-of-interest statement.pdf
Copyright License Agreement 63549-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 63549-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 63549-Institutional review board statement.pdf
Peer-review Report 63549-Peer-review(s).pdf
Scientific Misconduct Check 63549-Bing-Ma YJ-1.jpg
Scientific Misconduct Check 63549-Bing-Liu M-2.png
Scientific Editor Work List 63549-Scientific editor work list.pdf