Publication Name	World Journal of Hepatology
Manuscript ID	64068
Country	Greece

Received	2021-02-08 07:29
Peer-Review Started	2021-02-08 07:33
First Decision by Editorial Office Director	2021-03-29 00:03
Return for Revision	2021-04-06 06:38
Revised	2021-04-14 08:39
Publication Fee Transferred
Second Decision by Editor	2021-12-31 03:40
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2021-12-31 22:24
Articles in Press	2021-12-31 22:24
Edit the Manuscript by Language Editor	2021-12-19 22:32
Typeset the Manuscript	2022-01-18 04:34
Publish the Manuscript Online	2022-01-21 08:16

ISSN	1948-5182 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Hepatitis C virus: A critical approach to who really needs treatment
Manuscript Source	Invited Manuscript
All Author List	Elias Kouroumalis and Argryro Voumvouraki
Funding Agency and Grant Number
Corresponding Author	Elias Kouroumalis, MD, PhD, Emeritus Professor, Department of Gastroenterology, University of Crete Medical School, Voutes, Heraklion 71500, Crete, Greece. kouroumi@uoc.gr
Key Words	Hepatitis C, Comorbidities, Screening and treatment policy; Hepatitis C virus; Review
Core Tip	Elimination of hepatitis C virus (HCV) by 2030 according to the World Health Organization policy seems highly unlikely because of the funding re-direction due to the coronavirus disease 2019 pandemic. It is important therefore to re-evaluate the treatment policies based on a more realistic and feasible approach. HCV disease has a very prolonged natural course, and even HCV-related cirrhosis has a lower mortality compared to other cirrhosis etiologies. However, liver related morbidity and mortality is increased when certain comorbidities accompany the initial HCV infection. A review of the current knowledge allows for a more or less accurate identification of these comorbidities. Therefore, an eradication program is proposed based on screening and treating only these particular groups.
Publish Date	2022-01-21 08:16
Citation	Kouroumalis E, Voumvouraki A. HCV: Who really needs treatment. A critical approach. World J Hepatol 2022; 14(1): 1-44
URL	https://www.wjgnet.com/1948-5182/full/v14/i1/1.htm
DOI	https://dx.doi.org/10.4254/wjh.v14.i1.1

Full Article (PDF)	WJH-14-1.pdf
Full Article (Word)	WJH-14-1.docx
Manuscript File	64068_Auto_edited-ML-Filipodia.docx
Answering Reviewers	64068-Answering reviewers.pdf
Audio Core Tip	64068-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	64068-Conflict-of-interest statement.pdf
Copyright License Agreement	64068-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	64068-Language certificate.pdf
Peer-review Report	64068-Peer-review(s).pdf
Scientific Misconduct Check	64068-Bing-Liu M-2.PNG
Scientific Editor Work List	64068-Scientific editor work list.pdf
CrossCheck Report	64068-CrossCheck report.pdf