Publication Name	World Journal of Clinical Oncology
Manuscript ID	64152
Country	United Kingdom

Received	2021-02-09 20:36
Peer-Review Started	2021-02-09 20:44
To Make the First Decision
Return for Revision	2021-03-31 04:55
Revised	2021-04-06 15:26
Second Decision	2021-06-02 11:29
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-06-02 13:02
Articles in Press	2021-06-02 13:02
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2021-06-15 04:26
Publish the Manuscript Online	2021-06-21 06:41

ISSN	2218-4333 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Oncology
Manuscript Type	Meta-Analysis
Article Title	Phytochemically rich dietary components and the risk of colorectal cancer: A systematic review and meta-analysis of observational studies
Manuscript Source	Invited Manuscript
All Author List	Pia Borgas, Guadalupe Gonzalez, Kirill Veselkov and Reza Mirnezami
Funding Agency and Grant Number
Corresponding Author	Reza Mirnezami, FRCS, MBBS, PhD, Senior Lecturer, Surgeon, Department of Colorectal Surgery, Royal Free Hospital, Pond Street, Hampstead, London NW3 2QG, United Kingdom. reza.mirnezami@nhs.net
Key Words	Colorectal cancer; Disease prevention; Diet; Risk; Nutrigenomics; Meta-analysis
Core Tip	Personalized nutrition and protective diets and lifestyles represent a key cancer research priority. Herein we present a systematic review and meta-analysis on the potential protective role of five common phytochemically rich dietary components (nuts, cruciferous vegetables, citrus fruits, garlic and tomatoes) in reducing colorectal cancer (CRC) risk. Results show that increased dietary consumption of cruciferous vegetables, citrus fruits, garlic and tomatoes is associated with reduced CRC risk. Active components of these may interact with certain genes to exert this anticarcinogenic effect, highlighting the potential for developing precision nutrition strategies for CRC prevention.
Publish Date	2021-06-21 06:41
Citation	Borgas P, Gonzalez G, Veselkov K, Mirnezami R. Phytochemically rich dietary components and the risk of colorectal cancer: A systematic review and meta-analysis of observational studies. World J Clin Oncol 2021; 12(6): 482-499
URL	https://www.wjgnet.com/2218-4333/full/v12/i6/482.htm
DOI	https://dx.doi.org/10.5306/wjco.v12.i6.482

Full Article (PDF)	WJCO-12-482.pdf
Full Article (Word)	WJCO-12-482.docx
PRISMA 2009 Checklist	64152-PRISMA-2009-Checklist-revision.pdf
Manuscript File	64152_Auto_Edited-ZMG.docx
Answering Reviewers	64152-Answering reviewers.pdf
Audio Core Tip	64152-Audio core tip.mp3
Biostatistics Review Certificate	64152-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	64152-Conflict-of-interest statement.pdf
Copyright License Agreement	64152-Copyright license agreement.pdf
Supplementary Material	64152-Supplementary material.pdf
Peer-review Report	64152-Peer-review(s).pdf
Scientific Misconduct Check	64152-Bing-Wang JL-1.jpg
Scientific Misconduct Check	64152-Scientific misconduct check.pdf
Scientific Editor Work List	64152-Scientific editor work list.pdf