| ISSN |
2220-3206 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Psychiatry |
| Manuscript Type |
Minireviews |
| Article Title |
Genetics of adult attachment: An updated review of the literature
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Leire Erkoreka, Mercedes Zumarraga, Aurora Arrue, M Isabel Zamalloa, Ainara Arnaiz, Olga Olivas, Teresa Moreno-Calle, Estela Saez, Jon Garcia, Elena Marin, Noemi Varela, Ana Gonzalez-Pinto and Nieves Basterreche |
| Funding Agency and Grant Number |
|
| Corresponding Author |
Leire Erkoreka, MD, PhD, Associate Chief Physician, Department of Psychiatry, Galdakao-Usansolo Hospital, Osakidetza Basque Health Service, Labeaga Auzoa 46A, Galdakao 48960, Spain. leire.erkorekagonzalez@osakidetza.eus |
| Key Words |
Genetics; Adult attachment; Oxytocin; Dopamine; Serotonin; Brain-derived neurotrophic factor; Methylation |
| Core Tip |
Attachment style influences adult cognitive, emotional and interpersonal functioning. Despite its relationship with early experiences, it is a malleable tendency that is shaped throughout the development. Genetic research indicates that up to 45% of the variability in anxious and 39% in avoidant adult attachment style could be explained by genetic causes. A narrative review is conducted analyzing the existing literature regarding the implication of candidate genes, with vulnerability and differential susceptibility approaches. We highlight the lack of genome-wide studies and scarcity of epigenetic investigation, concluding that further research is needed to clarify the etiological role of genetics on adult attachment. |
| Publish Date |
2021-09-15 10:23 |
| Citation |
Erkoreka L, Zumarraga M, Arrue A, Zamalloa MI, Arnaiz A, Olivas O, Moreno-Calle T, Saez E, Garcia J, Marin E, Varela N, Gonzalez-Pinto A, Basterreche N. Genetics of adult attachment: An updated review of the literature. World J Psychiatr 2021; 11(9): 530-542 |
| URL |
https://www.wjgnet.com/2220-3206/full/v11/i9/530.htm |
| DOI |
https://dx.doi.org/10.5498/wjp.v11.i9.530 |
