Publication Name	World Journal of Stem Cells
Manuscript ID	64872
Country	United States

Received	2021-02-25 14:57
Peer-Review Started	2021-02-25 15:05
To Make the First Decision
Return for Revision	2021-04-20 02:10
Revised	2021-04-30 17:46
Second Decision	2021-07-29 02:54
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-07-29 06:53
Articles in Press	2021-07-29 06:53
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2021-08-05 01:13
Publish the Manuscript Online	2021-08-20 05:46

ISSN	1948-0210 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Research & Experimental Medicine
Manuscript Type	Minireviews
Article Title	Effects of radiation and chemotherapy on adipose stem cells: Implications for use in fat grafting in cancer patients
Manuscript Source	Invited Manuscript
All Author List	Rebecca Platoff, Miguel A Villalobos, Ashleigh Rapp Hagaman, Yuan Liu, Martha Matthews, Michael E DiSanto, Jeffrey P Carpenter and Ping Zhang
Funding Agency and Grant Number
Corresponding Author	Ping Zhang, DDS, PhD, Assistant Professor, Department of Surgery, Cooper University Health Care, 401 Haddon Avenue, Camden, NJ 08103, United States. zhang-ping@cooperhealth.edu
Key Words	Fat grafting; Breast reconstruction; Stem cells; Breast cancer; Radiation; Chemotherapy
Core Tip	Breast reconstruction with fat grafting after surgery is a major therapy that is enhanced by the use of autologous adipose-derived stem cells (ASCs) following surgery for breast cancer. Emerging studies suggest that cancer treatment therapies have a cytotoxic effect that may limit stem cell cellular functions. In this review, we summarize our work on evaluating the functional recovery potential of autologous ASCs in patients post-radiation or chemotherapy. In addition, we provide evidence that ASCs may represent a novel and effective cellular mechanism for enhancing fat grafting and reconstruction outcomes especially in those patients with cancer.
Publish Date	2021-08-20 05:46
Citation	Platoff R, Villalobos MA, Hagaman AR, Liu Y, Matthews M, DiSanto ME, Carpenter JP, Zhang P. Effects of radiation and chemotherapy on adipose stem cells: Implications for use in fat grafting in cancer patients. World J Stem Cells 2021; 13(8): 1084-1093
URL	https://www.wjgnet.com/1948-0210/full/v13/i8/1084.htm
DOI	https://dx.doi.org/10.4252/wjsc.v13.i8.1084

Full Article (PDF)	WJSC-13-1084.pdf
Full Article (Word)	WJSC-13-1084.docx
Manuscript File	64872_Auto_Edited-JPY.docx
Answering Reviewers	64872-Answering reviewers.pdf
Audio Core Tip	64872-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	64872-Conflict-of-interest statement.pdf
Copyright License Agreement	64872-Copyright license agreement.pdf
Peer-review Report	64872-Peer-review(s).pdf
Scientific Misconduct Check	64872-Scientific misconduct check.pdf
Scientific Editor Work List	64872-Scientific editor work list.pdf