Publication Name	World Journal of Clinical Infectious Diseases
Manuscript ID	65056
Country	China

Received	2021-02-27 12:05
Peer-Review Started	2021-02-27 12:20
To Make the First Decision
Return for Revision	2021-03-31 05:32
Revised	2021-04-03 14:30
Second Decision	2021-09-09 03:22
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2021-09-10 09:32
Articles in Press	2021-09-10 09:32
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-10-26 18:04
Typeset the Manuscript	2021-11-02 00:47
Publish the Manuscript Online	2021-11-02 08:42

ISSN	2220-3176 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Infectious Diseases
Manuscript Type	Meta-Analysis
Article Title	Lymphocyte count predicts the severity of COVID-19: Evidence from a meta-analysis
Manuscript Source	Unsolicited Manuscript
All Author List	Yi-Si Zhao and Ying-Xi Yu
Funding Agency and Grant Number
Corresponding Author	Yi-Si Zhao, MM, Doctor, Doctor, Department of Critical Care Medicine, The First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi road, Yuzhong District, Chongqing 400016, China. 476663973@qq.com
Key Words	COVID-19; Lymphocyte count; Coronavirus; Severe of disease; Meta-analysis
Core Tip	Lymphocyte count reflects immune function and inflammatory state of body with infectious disease. Severe acute respiratory syndrome coronavirus 2 spreads and invades through respiratory mucosa, triggers a series of immune responses and induces cytokine storm in vivo, resulting in changes in immune components such as lymphocytes. Previous studies have shown that the decrease in lymphocyte count can be used as an indicator of severity for both severe acute respiratory syndrome and Middle East respiratory syndrome, both of which are coronavirus infections. Therefore, this paper systematically reviews and meta-analysis the literature evaluating the diagnostic and prognostic utility of the lymphocyte count in patients with viral pneumonia by coronavirus infections.
Publish Date	2021-11-02 08:42
Citation	Zhao YS, Yu YX. Lymphocyte count predicts the severity of COVID-19: Evidence from a meta-analysis. World J Clin Infect Dis 2021; 11(3): 49-59
URL	https://www.wjgnet.com/2220-3176/full/v11/i3/49.htm
DOI	https://dx.doi.org/10.5495/wjcid.v11.i3.49

Full Article (PDF)	WJCID-11-49.pdf
Full Article (Word)	WJCID-11-49.docx
PRISMA 2009 Checklist	65056-PRISMA-2009-Checklist-revision.doc
Manuscript File	65056_Auto_Edited_Kerr C_Clear Copy.docx
Answering Reviewers	65056-Answering reviewers.pdf
Audio Core Tip	65056-Audio core tip.m4a
Biostatistics Review Certificate	65056-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	65056-Conflict-of-interest statement.pdf
Copyright License Agreement	65056-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	65056-Language certificate.pdf
Supplementary Material	65056-Supplementary material.pdf
Peer-review Report	65056-Peer-review(s).pdf
Scientific Misconduct Check	65056-Bing-Ma YJ-1.jpg
Scientific Misconduct Check	65056-Bing-Liu M-2.png
Scientific Editor Work List	65056-Scientific editor work list.pdf
CrossCheck Report	65056-CrossCheck report.pdf