Publication Name	World Journal of Diabetes
Manuscript ID	65159
Country	Italy

Received	2021-02-28 18:35
Peer-Review Started	2021-02-28 18:52
To Make the First Decision
Return for Revision	2021-03-30 02:13
Revised	2021-04-01 22:07
Second Decision	2021-11-02 03:56
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2021-11-03 01:30
Articles in Press	2021-11-03 01:30
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-10-28 17:11
Typeset the Manuscript	2021-12-10 08:11
Publish the Manuscript Online	2021-12-16 07:46

ISSN	1948-9358 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Endocrinology & Metabolism
Manuscript Type	Minireviews
Article Title	Omics era in type 2 diabetes: From childhood to adulthood
Manuscript Source	Invited Manuscript
All Author List	Antonio Paride Passaro, Pierluigi Marzuillo, Stefano Guarino, Federica Scaglione, Emanuele Miraglia del Giudice and Anna Di Sessa
Funding Agency and Grant Number
Corresponding Author	Anna Di Sessa, MD, PhD, Research Fellow, Department of Woman, Child and of General and Specialized Surgery, Università degli Studi della Campania “Luigi Vanvitelli”, Via Luigi De Crecchio 2, Napoli 80138, Italy. anna.disessa@libero.it
Key Words	Omics; Diabetes; Children; Adults; Type 2 diabetes
Core Tip	Type 2 diabetes (T2D) represents an emerging health concern worldwide. Its cardiometabolic burden affects both adults and children. Given the alarming rise of pediatric obesity, a high prevalence of T2D has been reported already in childhood. Although lifestyle modifications and metformin represent the first-line therapy for T2D, several drugs are available and others are being studied. In this view, an attractive therapeutic tool derives from omics studies. Based on T2D pathophysiology, these analyses highlighted the role of different lipids and metabolites closely intertwined with insulin signaling pathways as potential biomarkers for T2D, by paving the way for novel treatment strategies.
Publish Date	2021-12-16 07:46
Citation	Passaro AP, Marzuillo P, Guarino S, Scaglione F, Miraglia del Giudice E, Di Sessa A. Omics era in type 2 diabetes: From childhood to adulthood. World J Diabetes 2021; 12(12): 2027-2035
URL	https://www.wjgnet.com/1948-9358/full/v12/i12/2027.htm
DOI	https://dx.doi.org/10.4239/wjd.v12.i12.2027

Full Article (PDF)	WJD-12-2027.pdf
Full Article (Word)	WJD-12-2027.docx
Manuscript File	65159_Auto_Edited-CCG-Kerr C.docx
Answering Reviewers	65159-Answering reviewers.pdf
Audio Core Tip	65159-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	65159-Conflict-of-interest statement.pdf
Copyright License Agreement	65159-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	65159-Language certificate.pdf
Peer-review Report	65159-Peer-review(s).pdf
Scientific Misconduct Check	65159-Bing-Gao CC-2.png
Scientific Editor Work List	65159-Scientific editor work list.pdf
CrossCheck Report	65159-CrossCheck report.pdf