Publication Name	World Journal of Biological Chemistry
Manuscript ID	66556
Country	India

Received	2021-03-30 11:41
Peer-Review Started	2021-03-30 11:48
To Make the First Decision
Return for Revision	2021-05-16 13:12
Revised	2021-05-21 05:06
Second Decision	2021-11-25 05:35
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-11-26 02:30
Articles in Press	2021-11-26 02:30
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-11-05 02:50
Typeset the Manuscript	2021-11-26 03:23
Publish the Manuscript Online	2021-12-14 05:28

ISSN	1949-8454 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Rheumatology
Manuscript Type	Meta-Analysis
Article Title	Remission is not maintained over 2 years with hematopoietic stem cell transplantation for rheumatoid arthritis: A systematic review with meta-analysis
Manuscript Source	Invited Manuscript
All Author List	Sathish Muthu, Madhan Jeyaraman, Rajni Ranjan and Saurabh Kumar Jha
Funding Agency and Grant Number
Corresponding Author	Sathish Muthu, MS, Assistant Professor, Research Fellow, School of Engineering and Technology, Sharda University, Greater Noida, Delhi 201306, Uttar Pradesh, India. drsathishmuthu@gmail.com
Key Words	Hematopoietic stem cell; Rheumatoid arthritis; Disease-modifying anti-rheumatic drug; Biological therapy; Systematic review; Meta-analysis
Core Tip	With the rising resistance to the traditional disease-modifying anti-rheumatic drugs and targeted biological therapy, we performed this systematic review and meta-analysis to evaluate the role of hematopoietic stem cell therapy in the management of rheumatoid arthritis. Literature on the effectiveness of the intervention is encouraging with significant improvement till 2 years post-therapy. We have explored the ambiguity in the current treatment methods in hematopoietic stem cell therapy that needs further exploration to optimize the results out of this treatment modality.
Publish Date	2021-12-14 05:28
Citation	Muthu S, Jeyaraman M, Ranjan R, Jha SK. Remission is not maintained over 2 years with hematopoietic stem cell transplantation for rheumatoid arthritis: A systematic review with meta-analysis. World J Biol Chem 2021; 12(6) 114-130
URL	https://www.wjgnet.com/1949-8454/full/v12/i6/114.htm
DOI	https://dx.doi.org/10.4331/wjbc.v12.i6.114

Full Article (PDF)	WJBC-12-114.pdf
Full Article (Word)	WJBC-12-114.docx
Manuscript File	66556_Auto_Edited-YJM_WangTQ.docx
Answering Reviewers	66556-Answering reviewers.pdf
Audio Core Tip	66556-Audio core tip.aac
Biostatistics Review Certificate	66556-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	66556-Conflict-of-interest statement.pdf
Copyright License Agreement	66556-Copyright license agreement.pdf
Supplementary Material	66556-Supplementary material.pdf
Peer-review Report	66556-Peer-review(s).pdf
Scientific Editor Work List	66556-Scientific editor work list.pdf