Publication Name	World Journal of Clinical Oncology
Manuscript ID	66871
Country	Türkiye

Received	2021-04-08 05:08
Peer-Review Started	2021-04-08 05:11
To Make the First Decision
Return for Revision	2021-06-16 04:51
Revised	2021-06-21 11:23
Second Decision	2022-01-10 05:44
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2022-01-10 22:58
Articles in Press	2022-01-10 22:58
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-02-16 13:47
Publish the Manuscript Online	2022-02-23 09:24

ISSN	2218-4333 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Oncology
Manuscript Type	Minireviews
Article Title	Optimal timing of thoracic irradiation for limited stage small cell lung cancer: Current evidence and future prospects
Manuscript Source	Invited Manuscript
All Author List	Omer Sager, Ferrat Dincoglan, Selcuk Demiral, Hakan Gamsiz, Bora Uysal, Fatih Ozcan, Onurhan Colak, Esra Gumustepe, Yelda Elcim, Esin Gundem, Bahar Dirican and Murat Beyzadeoglu
Funding Agency and Grant Number
Corresponding Author	Omer Sager, MD, Associate Professor, Gulhane Medical Faculty Department of Radiation Oncology, University of Health Sciences, Gn Dr Tevfik Saglam Street, Ankara 0090, Türkiye. omersager@gmail.com
Key Words	Small cell lung cancer; Thoracic irradiation; Limited stage small cell lung cancer; Timing of thoracic radiation therapy; Thoracic radiation therapy
Core Tip	There has been extensive effort to establish optimal timing of thoracic radiation therapy (TRT) in limited stage small cell lung cancer (LS-SCLC) management. While late TRT may have utility for management of LS-SCLC patients who may not tolerate curative-intent upfront chest irradiation due to excessive tumor burden at the outset, early TRT allows for exploiting the synergistic effect of chemoradiotherapy to eradicate as many tumor cells as possible in a shorter timeframe. Admittedly, differences in trial designs, definition of early and late TRT, patient selection criteria, administered chemotherapy regimens, treatment compliance, TRT dose and fractionation may affect treatment outcomes.
Publish Date	2022-02-23 09:24
Citation	Sager O, Dincoglan F, Demiral S, Gamsiz H, Uysal B, Ozcan F, Colak O, Gumustepe E, Elcim Y, Gundem E, Dirican B, Beyzadeoglu M. Optimal timing of thoracic irradiation for limited stage small cell lung cancer: Current evidence and future prospects. World J Clin Oncol 2022; 13(2): 116-124
URL	https://www.wjgnet.com/2218-4333/full/v13/i2/116.htm
DOI	https://dx.doi.org/10.5306/wjco.v13.i2.116

Full Article (PDF)	WJCO-13-116.pdf
Full Article (Word)	WJCO-13-116.docx
Manuscript File	66871_Auto_Edited.docx
Answering Reviewers	66871-Answering reviewers.pdf
Audio Core Tip	66871-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	66871-Conflict-of-interest statement.pdf
Copyright License Agreement	66871-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	66871-Language certificate.pdf
Peer-review Report	66871-Peer-review(s).pdf
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Scientific Editor Work List	66871-Scientific editor work list.pdf