Publication Name	World Journal of Hepatology
Manuscript ID	67167
Country	United Kingdom

Received	2021-04-17 11:35
Peer-Review Started	2021-04-17 11:39
First Decision by Editorial Office Director	2021-07-27 02:23
Return for Revision	2021-07-27 02:23
Revised	2021-08-01 07:23
Publication Fee Transferred
Second Decision by Editor	2021-10-27 09:17
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2021-10-27 21:24
Articles in Press	2021-10-27 21:24
Edit the Manuscript by Language Editor
Typeset the Manuscript	2021-12-16 11:06
Publish the Manuscript Online	2021-12-27 05:24

ISSN	1948-5182 (online)
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Category	Gastroenterology & Hepatology
Manuscript Type	Opinion Review
Article Title	Non-alcoholic fatty liver disease in irritable bowel syndrome: More than a coincidence?
Manuscript Source	Invited Manuscript
All Author List	Huw Purssell, Peter J Whorwell, Varinder S Athwal and Dipesh H Vasant
Funding Agency and Grant Number
Corresponding Author	Dipesh H Vasant, MBChB, MRCP, PhD, Senior Lecturer, Neurogastroenterology Unit，Department of Gastroenterology, Manchester University NHS Foundation Trust，Wythenshawe Hospital, Southmoor Road, Manchester M23 9LT, United Kingdom. dipesh.vasant@manchester.ac.uk
Key Words	Irritable bowel syndrome; Non-alcoholic fatty liver disease; Metabolic syndrome; Obesity; Prevalence; Pathophysiology
Core Tip	Irritable bowel syndrome (IBS) and non-alcoholic fatty liver disease (NAFLD) are amongst the most common gastrointestinal and liver conditions encountered in primary and secondary care. There has been interest in the apparent co-incidence of NAFLD in patients with IBS mainly driven by improved understanding of their shared risk factors and pathophysiology. In this paper we summarize the shared risk factors which include; overlapping nutritional and dietary factors as well as shared putative mechanisms of pathophysiology. Physicians should be aware of the possibility of co-existence of IBS and NAFLD and consider investigating patients with IBS or NAFLD with clinical features of the other condition.
Publish Date	2021-12-27 05:24
Citation	Purssell H, Whorwell PJ, Athwal VS, Vasant DH. Non-alcoholic fatty liver disease in irritable bowel syndrome: More than a coincidence? World J Hepatol 2021; 13(12): 1816-1827
URL	https://www.wjgnet.com/1948-5182/full/v13/i12/1816.htm
DOI	https://dx.doi.org/10.4254/wjh.v13.i12.1816

Full Article (PDF)	WJH-13-1816.pdf
Full Article (Word)	WJH-13-1816.docx
Manuscript File	67167_Auto_Edited.docx
Answering Reviewers	67167-Answering reviewers.pdf
Audio Core Tip	67167-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	67167-Conflict-of-interest statement.pdf
Copyright License Agreement	67167-Copyright license agreement.pdf
Peer-review Report	67167-Peer-review(s).pdf
Scientific Misconduct Check	67167-Bing-Wang JJ-2.png
Scientific Editor Work List	67167-Scientific editor work list.pdf
CrossCheck Report	67167-CrossCheck report.pdf