BPG is committed to discovery and dissemination of knowledge
Featured Articles
12/28/2021 11:18:19 AM | Browse: 525 | Download: 1352
 |
Received |
|
2021-08-18 04:44 |
|
Peer-Review Started |
|
2021-08-18 04:48 |
|
First Decision by Editorial Office Director |
|
2021-11-02 03:47 |
|
Return for Revision |
|
2021-11-06 07:59 |
|
Revised |
|
2021-11-13 17:54 |
 |
Publication Fee Transferred |
|
|
|
Second Decision by Editor |
|
2021-12-24 04:45 |
|
Second Decision by Editor-in-Chief |
|
|
|
Final Decision by Editorial Office Director |
|
2021-12-24 08:20 |
|
Articles in Press |
|
2021-12-24 08:20 |
|
Edit the Manuscript by Language Editor |
|
2021-12-14 10:02 |
|
Typeset the Manuscript |
|
2021-12-26 15:41 |
|
Publish the Manuscript Online |
|
2021-12-28 09:18 |
| ISSN |
2308-3840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Clinical Neurology |
| Manuscript Type |
Meta-Analysis |
| Article Title |
Efficacy and safety of fingolimod in stroke: A systemic review and meta-analysis
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Kai Zhao, Yu Guo, Ming-Fei Yang and Qiang Zhang |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Project of Science and Technology Department of Qinghai Province |
2020-ZJ-774 |
| National Key R&D Program of China |
2018YFC1312601 |
|
| Corresponding Author |
Qiang Zhang, MD, PhD, Chief Doctor, Surgeon, Department of Neurosurgery, Qinghai Provincial People's Hospital, No. 2 Gonghe Road, Xining 810007, Qinghai Province, China. zhangqiang691212@163.com |
| Key Words |
Acute ischemic stroke; Intracerebral hemorrhage; Fingolimod; Meta-analysis; Treatment |
| Core Tip |
Brain tissue injury in stroke patients involves inflammation around the infarction lesion or hematoma, which is an important reason for disease deterioration and can result in a poor prognosis. Our systemic review and meta-analysis of recent randomized controlled trials found that fingolimod might improve neurological function in stroke patients by reducing lymphocyte infiltration in the brain effectively; however, we did not find the evidence that fingolimod could promote infarction lesion or hematoma absorption. In general, oral fingolimod (0.5 mg/d, 3 consecutive days) was safe in stroke patients except for some rare severe adverse events. |
| Publish Date |
2021-12-28 09:18 |
| Citation |
Zhao K, Guo Y, Yang MF, Zhang Q. Efficacy and safety of fingolimod in stroke: A systemic review and meta-analysis. World J Meta-Anal 2021; 9(6): 585-597
|
| URL |
https://www.wjgnet.com/2308-3840/full/v9/i6/585.htm |
| DOI |
https://dx.doi.org/10.13105/wjma.v9.i6.585 |
All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.
