Publication Name	World Journal of Cardiology
Manuscript ID	71148
Country	United States

Received	2021-08-30 02:38
Peer-Review Started	2021-08-30 02:38
To Make the First Decision
Return for Revision	2022-04-07 02:38
Revised	2022-04-25 17:08
Second Decision	2022-06-10 03:05
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2022-06-17 23:03
Articles in Press	2022-06-17 23:03
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-07-17 11:46
Publish the Manuscript Online	2022-07-20 02:45

ISSN	1949-8462 (online)
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Category	Nutrition & Dietetics
Manuscript Type	Observational Study
Article Title	Vitamin d deficiency and metabolic syndrome: The joint effect on cardiovascular and all-cause mortality in the United States adults
Manuscript Source	Invited Manuscript
All Author List	Longjian Liu, Saishi Cui, Stella L Volpe, Nathalie S May, Deeptha Sukumar, Rose Ann DiMaria-Ghalili and Howard J Eisen
Funding Agency and Grant Number
Corresponding Author	Longjian Liu, MD, MSc, PhD, Doctor, Department of Epidemiology and Biostatistics, Dornsife School of Public Health, Drexel University, 3215 Market Street, Philadelphia, PA 19104, United States. ll85@drexel.edu
Key Words	Joint effect; Serum 25 hydroxyvitamin D concentration; Metabolic syndrome; Cardiovascular and all-cause mortality; Cox model and machine learning
Core Tip	To investigate the long-term effect of vitamin D deficiency and metabolic syndrome on the risk of cardiovascular disease and all-cause mortality using a nationally representative sample. Standard measurements of the study exposures, co-variables and outcomes are processed. Multivariate Cox's proportional hazards regression analysis was used to prospectively test the associations between the exposures and outcomes. Classification and regression tree for machine learning was applied to classify subjects with higher risk of lower serum vitamin D concentrations.
Publish Date	2022-07-20 02:45
Citation	Liu L, Cui S, Volpe SL, May NS, Sukumar D, DiMaria-Ghalili RA, Eisen HJ. Vitamin d deficiency and metabolic syndrome: The joint effect on cardiovascular and all-cause mortality in the United States adults. World J Cardiol 2022; 14(7): 411-426
URL	https://www.wjgnet.com/1949-8462/full/v14/i7/411.htm
DOI	https://dx.doi.org/10.4330/wjc.v14.i7.411

Full Article (PDF)	WJC-14-411.pdf
Full Article (Word)	WJC-14-411.docx
Manuscript File	71148_Auto_Edited-YJM-LS.docx
Answering Reviewers	71148-Answering reviewers.pdf
Audio Core Tip	71148-Audio core tip.m4a
Biostatistics Review Certificate	71148-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	71148-Conflict-of-interest statement.pdf
Copyright License Agreement	71148-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s)	71148-Informed consent statement.pdf
Institutional Review Board Approval Form or Document	71148-Institutional review board statement.pdf
Supplementary Material	71148-Supplementary material.pdf
Peer-review Report	71148-Peer-review(s).pdf
Scientific Editor Work List	71148-Scientific editor work list.pdf