Publication Name	World Journal of Gastroenterology
Manuscript ID	72785
Country	Singapore

Received	2021-11-03 05:33
Peer-Review Started	2021-11-03 05:34
To Make the First Decision
Return for Revision	2021-12-26 21:32
Revised	2022-01-03 16:11
Second Decision	2022-03-22 06:37
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2022-03-27 05:31
Articles in Press	2022-03-27 05:31
Publication Fee Transferred
Edit the Manuscript by Language Editor	2022-03-18 23:03
Typeset the Manuscript	2022-04-01 14:15
Publish the Manuscript Online	2022-04-29 06:42

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Pediatrics
Manuscript Type	Retrospective Cohort Study
Article Title	Epidemiological characteristics of Asian children with inflammatory bowel disease at diagnosis: Insights from an Asian-Pacific multi-centre registry network
Manuscript Source	Invited Manuscript
All Author List	James Guoxian Huang, Yoko Kin Yoke Wong, Kee Seang Chew, Pornthep Tanpowpong, Karen Sophia Calixto Mercado, Almida Reodica, Shaman Rajindrajith, Kai-Chi Chang, Yen-Hsuan Ni, Suporn Treepongkaruna, Way-Seah Lee and Marion Margaret Aw
Funding Agency and Grant Number
Corresponding Author	James Guoxian Huang, MBBS, Assistant Professor, Doctor, Staff Physician, Khoo Teck Puat-National University Children's Medical Institute, National University Health System, NUHS Tower Block Level 12, 1E Kent Ridge Road, Singapore 119228, Singapore. james_huang@nuhs.edu.sg
Key Words	Asia; Inflammatory bowel disease; Paediatrics; Crohn’s disease; Ulcerative colitis; Registry
Core Tip	We describe the presenting features of paediatric inflammatory bowel disease (IBD) in 7 paediatric gastroenterology centers across six Asia-Pacific regions via a centrally-hosted electronic data capture platform. Clinical, endoscopic and radiologic data of 311 paediatric patients diagnosed with IBD between 1995 and 2019 were extracted. The ratio of Crohn’s (CD):Ulcerative colitis:IBD-Unclassified was 55.9%:38.3%:5.8%. The mean age was 9.07 years with a high proportion of very early onset IBD (VEO-IBD) and EO-IBD. An over-representation of the Indian/South Asian ethnic group was observed in the multiethnic subpopulations of Singapore and Malaysia. Patients of Indian/South Asian ethnicity were also most likely to present with symptomatic perianal CD.
Publish Date	2022-04-29 06:42
Citation	Huang JG, Wong YKY, Chew KS, Tanpowpong P, Calixto Mercado KS, Reodica A, Rajindrajith S, Chang KC, Ni YH, Treepongkaruna S, Lee WS, Aw MM. Epidemiological characteristics of Asian children with inflammatory bowel disease at diagnosis: Insights from an Asian-Pacific multi-centre registry network. World J Gastroenterol 2022; 28(17): 1830-1844
URL	https://www.wjgnet.com/1007-9327/full/v28/i17/1830.htm
DOI	https://dx.doi.org/10.3748/wjg.v28.i17.1830

Full Article (PDF)	WJG-28-1830.pdf
Full Article (Word)	WJG-28-1830.docx
Manuscript File	72785_Auto_Edited-JJW-Filipodia.docx
Answering Reviewers	72785-Answering reviewers.pdf
Audio Core Tip	72785-Audio core tip.mp3
Biostatistics Review Certificate	72785-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	72785-Conflict-of-interest statement.pdf
Copyright License Agreement	72785-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s)	72785-Informed consent statement.pdf
Institutional Review Board Approval Form or Document	72785-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	72785-Language certificate.pdf
Peer-review Report	72785-Peer-review(s).pdf
Scientific Misconduct Check	72785-Bing-Wang JJ-2.png
Scientific Editor Work List	72785-Scientific editor work list.pdf