Publication Name	World Journal of Gastroenterology
Manuscript ID	72788
Country	South Korea

Received	2021-10-28 04:26
Peer-Review Started	2021-10-28 04:28
To Make the First Decision
Return for Revision	2021-12-12 06:07
Revised	2021-12-17 06:57
Second Decision	2022-01-17 05:39
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2022-01-20 04:00
Articles in Press	2022-01-20 04:00
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-02-07 02:41
Publish the Manuscript Online	2022-02-17 09:46

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Will the collaboration of surgery and external radiotherapy open new avenues for hepatocellular carcinoma with portal vein thrombosis?
Manuscript Source	Unsolicited Manuscript
All Author List	Jung Wan Choe, Hye Yoon Lee and Chai Hong Rim
Funding Agency and Grant Number	Funding Agency Grant Number National Research Fund of Korea NRF-2021R1I1A2047475
Corresponding Author	Chai Hong Rim, MD, PhD, Assistant Professor, Department of Radiation Oncology, Korea University Ansan Hospital, 123 Jeokgeum-ro, Danwon-gu, Ansan 15355, South Korea. crusion3@naver.com
Key Words	Surgery; Hepatocellular carcinoma; Radiotherapy; Systemic treatment
Core Tip	The prognosis of hepatocellular carcinoma with portal vein involvement is poor, and there had been few available local modalities. However, with the development of radiotherapy techniques, the 1-year survival rate has been reported to be close to 45%-50% after palliation. Recently, a surgical approach has also been attempted showing encouraging results. Furthermore, the combination of surgery and radiation therapy showed effective results in studies including randomized studies. The combination of these two modalities are expected to increase efficacy of treating hepatocellular carcinoma with portal invasion.
Publish Date	2022-02-17 09:46
Citation	Choe JW, Lee HY, Rim CH. Will the collaboration of surgery and external radiotherapy open new avenues for hepatocellular carcinoma with portal vein thrombosis? World J Gastroenterol 2022; 28(7): 704-714
URL	https://www.wjgnet.com/1007-9327/full/v28/i7/704.htm
DOI	https://dx.doi.org/10.3748/wjg.v28.i7.704

Full Article (PDF)	WJG-28-704.pdf
Full Article (Word)	WJG-28-704.docx
Manuscript File	72788_Auto_Edited.docx
Answering Reviewers	72788-Answering reviewers.pdf
Audio Core Tip	72788-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	72788-Conflict-of-interest statement.pdf
Copyright License Agreement	72788-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	72788-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate	72788-Language certificate.pdf
Peer-review Report	72788-Peer-review(s).pdf
Scientific Misconduct Check	72788-CrossCheck.jpg
Scientific Misconduct Check	72788-Bing-Gong ZM-2.png
Scientific Editor Work List	72788-Scientific editor work list.pdf