Publication Name	World Journal of Gastroenterology
Manuscript ID	72987
Country	China

Received	2021-11-25 10:52
Peer-Review Started	2021-11-25 10:54
To Make the First Decision
Return for Revision	2022-01-11 01:18
Revised	2022-01-18 12:30
Second Decision	2022-03-03 05:46
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2022-03-06 22:50
Articles in Press	2022-03-06 22:50
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-04-01 11:06
Publish the Manuscript Online	2022-04-15 08:25

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Basic Study
Article Title	Establishing a rabbit model of perianal fistulizing Crohn’s disease
Manuscript Source	Invited Manuscript
All Author List	Shuang-Shuang Lu, Wen-Jia Liu, Qiu-Ya Niu, Chun-Yan Huo, Yu-Qing Cheng, En-Jing Wang, Rong-Nan Li, Fang-Fang Feng, Yi-Ming Cheng, Rong Liu and Jin Huang
Funding Agency and Grant Number
Corresponding Author	Jin Huang, PhD, Chief Doctor, Gastroenterology Center, The Affiliated Changzhou Second People's Hospital of Nanjing Medical University, No. 68 Gehu Road, Wujin District, Changzhou 213000, Jiangsu , China. hj042153@hotmail.com
Key Words	Crohn’s disease; Perianal fistula; Model; Endoscopy; Histology
Core Tip	In this work, we improved the method of Crohn's disease (CD) colitis induction and successfully established a rabbit perianal fistula CD preclinical model, which was confirmed by endoscopy and pathology. The anatomy of this mid- to large-sized animal can simulate the human intestinal environment and tolerate examination and operation. This model may be used to assess perianal fistulizing CD treatments and their effectiveness.
Publish Date	2022-04-15 08:25
Citation	Lu SS, Liu WJ, Niu QY, Huo CY, Cheng YQ, Wang EJ, Li RN, Feng FF, Cheng YM, Liu R, Huang J. Establishing a rabbit model of perianal fistulizing Crohn’s disease. World J Gastroenterol 2022; 28(15): 1536-1547
URL	https://www.wjgnet.com/1007-9327/full/v28/i15/1536.htm
DOI	https://dx.doi.org/10.3748/wjg.v28.i15.1536

Full Article (PDF)	WJG-28-1536.pdf
Full Article (Word)	WJG-28-1536.docx
The ARRIVE Guidelines	72987-The-ARRIVE-Guidelines-revision.docx
Manuscript File	72987_Auto_Edited.docx
Answering Reviewers	72987-Answering reviewers.pdf
Audio Core Tip	72987-Audio core tip.aac
Biostatistics Review Certificate	72987-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	72987-Conflict-of-interest statement.pdf
Copyright License Agreement	72987-Copyright license agreement.pdf
Institutional Animal Care and Use Committee Approval Form or Document	72987-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document	72987-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	72987-Language certificate.pdf
Supplementary Material	72987-Supplementary material.pdf
Peer-review Report	72987-Peer-review(s).pdf
Scientific Editor Work List	72987-Scientific editor work list.pdf