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8/3/2022 8:55:07 AM | Browse: 19 | Download: 26
Publication Name World Journal of Gastroenterology
Manuscript ID 73730
Country/Territory Italy
Received
2021-12-03 16:04
Peer-Review Started
2021-12-03 16:05
To Make the First Decision
Return for Revision
2022-05-29 08:03
Revised
2022-06-06 16:21
Second Decision
2022-07-06 08:12
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-07-11 18:32
Articles in Press
2022-07-11 18:32
Publication Fee Transferred
Edit the Manuscript by Language Editor
2022-06-28 02:25
Typeset the Manuscript
2022-07-25 02:47
Publish the Manuscript Online
2022-08-03 07:54
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Minireviews
Article Title Clinical challenge for gastroenterologists–Gastrointestinal manifestations of systemic mastocytosis: A comprehensive review
Manuscript Source Invited Manuscript
All Author List Alessandra Elvevi, Elena Maria Elli, Martina Lucà, Miki Scaravaglio, Fabio Pagni, Stefano Ceola, Laura Ratti, Pietro Invernizzi and Sara Massironi
Funding Agency and Grant Number
Corresponding Author Sara Massironi, MD, PhD, Doctor, Gastroenterology Division, San Gerardo Hospital, University of Milano – Bicocca School of Medicine, Via G.B. Pergolesi 33 , Monza 20900, Italy. sara.massironi@libero.it
Key Words Systemic mastocytosis; Gastrointestinal involvement; Gastrointestinal symptoms
Core Tip Gastrointestinal (GI) involvement is frequent in systemic disease (SM); GI symptoms are frequent (second in frequency only to itching), being the main culprits of chronic disorders, and are a major determinant of quality of life. GI symptoms could be secondary both to mast cell (MC) mediator release and MC infiltration in the GI tract, causing organ dysfunction. Diagnosis of GI involvement in SM is based on clinical and endoscopic suspicion and histologic demonstration of MC infiltration in GI mucosa, using immunohistochemistry (i.e., CD117, tryptase, CD25). Symptomatic treatment is used to control mediators-release symptoms while cytoreductive therapies are necessary to reduce organ dysfunction secondary to MC infiltration and proliferation.
Publish Date 2022-08-03 07:54
Citation Elvevi A, Elli EM, Lucà M, Scaravaglio M, Pagni F, Ceola S, Ratti L, Invernizzi P, Massironi S. Clinical challenge for gastroenterologists–Gastrointestinal manifestations of systemic mastocytosis: A comprehensive review. World J Gastroenterol 2022; 28(29): 3767-3779
URL https://www.wjgnet.com/1007-9327/full/v28/i29/3767.htm
DOI https://dx.doi.org/10.3748/wjg.v28.i29.3767
Full Article (PDF) WJG-28-3767.pdf
Full Article (Word) WJG-28-3767.docx
Manuscript File 73730_Auto_Edited-YXJW-Filipodia-LS.docx
Answering Reviewers 73730-Answering reviewers.pdf
Audio Core Tip 73730-Audio core tip.aac
Conflict-of-Interest Disclosure Form 73730-Conflict-of-interest statement.pdf
Copyright License Agreement 73730-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate 73730-Language certificate.pdf
Peer-review Report 73730-Peer-review(s).pdf
Scientific Misconduct Check 73730-Bing-Wu YXJ-2.png
Scientific Editor Work List 73730-Scientific editor work list.pdf