Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	74065
Country	China

Received	2021-12-13 07:26
Peer-Review Started	2021-12-13 07:27
First Decision by Editorial Office Director	2022-01-27 07:33
Return for Revision	2022-01-27 08:19
Revised	2022-02-08 10:07
Publication Fee Transferred
Second Decision by Editor	2022-06-01 02:58
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2022-06-03 21:46
Articles in Press	2022-06-03 21:46
Edit the Manuscript by Language Editor	2022-05-18 10:03
Typeset the Manuscript	2022-06-21 07:35
Publish the Manuscript Online	2022-06-27 09:34

ISSN	1948-9366 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Oncology
Manuscript Type	Minireviews
Article Title	Transarterial chemoembolization failure/refractoriness: A scientific concept or pseudo-proposition
Manuscript Source	Invited Manuscript
All Author List	Shen Zhang, Bin-Yan Zhong, Lei Zhang, Wan-Sheng Wang and Cai-Fang Ni
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 81901847 Natural Science Foundation of Jiangsu Province BK20190177 Suzhou Science and Technology Youth Plan KJXW2018003
Corresponding Author	Cai-Fang Ni, MD, PhD, Chief Doctor, Department of Interventional Radiology, The First Affiliated Hospital of Soochow University, No. 899 Pinghai Road, Suzhou 215006, Jiangsu Province, China. szncf@suda.edu.cn
Key Words	Hepatocellular carcinoma; Transarterial chemoembolization; Failure; Refractoriness
Core Tip	The definitions in the current concept of transarterial chemoembolization (TACE) failure/refractoriness are not capable of guiding clinical practice. A persistent viable tumor lesion is a well-accepted item of TACE failure/refractoriness, but that is not the case when it comes to new lesions, portal vein tumor thrombosis or extrahepatic spread. Patients with recurrent hepatocellular carcinoma after TACE constitute a heterogenous group and the treatment modalities need to be individualized.
Publish Date	2022-06-27 09:34
Citation	Zhang S, Zhong BY, Zhang L, Wang WS, Ni CF. Transarterial chemoembolization failure/refractoriness: A scientific concept or pseudo-proposition. World J Gastrointest Surg 2022; 14(6): 528-537
URL	https://www.wjgnet.com/1948-9366/full/v14/i6/528.htm
DOI	https://dx.doi.org/10.4240/wjgs.v14.i6.528

Full Article (PDF)	WJGS-14-528.pdf
Full Article (Word)	WJGS-14-528.docx
Manuscript File	74065_Auto_Edited-YLC-Webster JR-LS.docx
Answering Reviewers	74065-Answering reviewers.pdf
Audio Core Tip	74065-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	74065-Conflict-of-interest statement.pdf
Copyright License Agreement	74065-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	74065-Language certificate.pdf
Peer-review Report	74065-Peer-review(s).pdf
Scientific Misconduct Check	74065-Bing-Chen YL-2.png
Scientific Editor Work List	74065-Scientific editor work list.pdf
CrossCheck Report	74065-CrossCheck report.pdf